Harald Reuter

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Harald Reuter (born March 25, 1934 in Düsseldorf ) is a German-Swiss physician and pharmacologist . He led basic research on calcium - ion channels by heart.

Life

Reuter studied medicine in Freiburg im Breisgau and Innsbruck and received his doctorate in 1960 at the Pharmacological Institute of the University of Mainz. He then worked as an assistant in Mainz and during this time also researched with Silvio Weidmann at the Physiological Institute of the University of Bern, where he dealt with electrophysiology of the heart. In 1965 he completed his habilitation in Mainz. In 1969 he became professor of pharmacology in Bern. From 1972 he was director of the Pharmacological Institute in Bern. 1983 to 1985 he was dean of the medical faculty. He retired in 1999. He was on several research stays in the United States (1967/68 Mayo Clinic as Assistant Professor, 1971, 1978/79 and 1986 at Yale University and 1992 to 2002 at Stanford University) and he was visiting professor in Japan (Japan Society for the Doctorate of Science), Great Britain (British Council), at the Biocenter Basel (1986/87) and China (Beijing).

He is committed to human rights, for which purpose he founded a commission within the framework of the Council of Scientific Academies in Switzerland (CASS).

Harald Reuter has been a Swiss citizen since 1987.

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Reuter's research concerns fundamental questions of cardiac function. In 1967 he described for the first time the inward flow of calcium through the cell membranes of the heart and how it is influenced by adrenaline. The calcium current is essential to the contraction of the heart and is influenced by drugs such as calcium antagonists . In 1968, together with N. Seitz, he first described the sodium / calcium exchange in the heart, which mainly transports calcium out of the heart cells and is essential for the functioning of the cardiac glycosides . Later he also dealt with calcium ion channels in the heart and in the nervous system. For example, he and his colleagues described the molecular regulation of the channels through which calcium flows into the heart cells by calmodulin . In a work with GW Beeler, he developed a theoretical model of the action potential on the heart. In later experiments with optical methods, in collaboration with colleagues at Stanford, he measured the circulation of neurotransmitter-containing vesicles in synapses of nerve cells. The release of neurotransmitters from the vesicles is fundamental for communication between nerve cells.

Honors and memberships

He is an elected member of the following academic academies: Academia Europaea (1989); European Academy of Sciences and Arts (1997); German Academy of Natural Scientists Leopoldina (1993); Académie Royale de Médecine de Belgique (honorary member) (2001); Swiss Academy of Medical Sciences (individual member (1995), honorary member (2010)); National Academy of Sciences (Foreign Member) (1997).

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Individual evidence

  1. ↑ Harald Reuter: The dependence of slow inward currents in Purkinje fibers on the extracellular calcium concentration. In: The Journal of Physiology . 192, 1967, pp. 479-492.
  2. ^ H. Reuter, N. Seitz: The dependence of calcium efflux from cardiac muscle on temperature and external ion composition. In: The Journal of Physiology. 195, 1968, pp. 451-470.
  3. ↑ Reuter H. u. a.:Properties of single calcium channels in cardiac cell cultures. In: Nature. 297, 1982, pp. 501-504.
  4. ^ Roger D. Zühlke et al .: Calmodulin supports both inactivation and facilitation of L-type ion channels. In: Nature. 399, 1999, pp. 159-162, doi: 10.1038 / 20200 .
  5. ^ GW Beeler, H. Reuter: Reconstruction of the action potential of ventricular myocardial fibers. In: The Journal of Physiology. 268, 1977, pp. 177-210.
  6. ^ TA Ryan, H. Reuter, et.al. "The kinetics of synaptic vesicle recycling measured at presynaptic boutons. In: Neuron. 11, 1993, pp. 713-724
  7. ↑ Seven honorary doctorates at the Dies Academicus of the University of Basel as part of the 550 year celebrations.  ( Page no longer available , search in web archives )  Info: The link was automatically marked as defective. Please check the link according to the instructions and then remove this notice. in: University of Basel. November 26, 2011.@1@ 2Template: Dead Link / www.unibas.ch  
  8. ↑ Member entry by Prof. Dr. Harald Reuter (with picture and CV) at the German Academy of Sciences Leopoldina , accessed on July 19, 2016.
personal data
SURNAME Reuter, Harald
BRIEF DESCRIPTION German medic
DATE OF BIRTH March 25, 1934
PLACE OF BIRTH Dusseldorf