Hartmut Redlich

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Hartmut Redlich (2017)

Hartmut G. Redlich (born September 19, 1943 in Wreschen near Posen ) is a German chemist ( organic chemistry ) who is a professor at the University of Münster and who deals with the chemistry of carbohydrates and the synthesis of natural substances .

Redlich acquired his diploma in 1970 in Hamburg and was founded in 1974 with Hans Paulsen at the University of Hamburg PhD ( synthesis of the four isomeric Methylaldgaroside: Structure determination of Methylaldgarosids B from Aldgamycin E ) and habilitated in 1983 in Hamburg ( Chiral building blocks of carbohydrates ). In 1985 he became a professor in Hamburg and in 1991 in Münster.

He dealt with the synthesis of enantiomerically pure natural products and in this context with the development of chiral building blocks for the synthesis from carbohydrates. When synthesizing natural substances, his goals included pheromones and antibiotics . Since the biologically important active ingredients are mostly stereoisomers , a stereoselective synthesis is of crucial importance. In addition to the development of methods of preparative carbohydrate chemistry, he is also concerned with novel reactions on and with carbohydrates .

Publications (selection)

  • H. Redlich, H.-J. Neumann, H. Paulsen: Radical deoxygenation of branched sugars with tri-n-butyl-tin hydride. Stereochemistry of the reaction, Chem. Ber. 110, 2911-2921 (1977), doi: 10.1002 / cber.19771100826 .
  • H. Redlich: Chiral building blocks from carbohydrates , habilitation thesis, University of Hamburg, 1983.
  • H. Redlich, W. Francke: Chirale building blocks from carbohydrates, Part 10 - Synthesis of enantiomerically pure 1,7-dioxaspiro [5.5] undecanes, a pheromone component of the olive fly (Dacus oleae) , Angew. Chem. 96, 506-507, doi: 10.1002 / anie.19840960717 .
  • H. Redlich, JB Lenfers, J. Kopf: Chiral cyclobutanones by [2 + 2] cycloaddition of dichloro ketene to carbohydrate enol ethers , Angew. Chem. 101 (1989) 764-765, doi: 10.1002 / anie.19891010612 .
  • H. Redlich, JB Lenfers, W. Bruns, S. Thormählen: Synthesis of (-) - Talaromycin A. The Use of the Ä2-Effect for Stereocontrol at Spiroacetalic Centers , Synthesis 1992, 1112.
  • W. Bruns, S. Horns, H. Redlich: Botrylactone Synthesis and Structure Revision: A Convergent Approach from d-Glucose , Synthesis 1995, 335-342, doi: 10.1055 / s-1995-3904 .
  • M. Schmeichel, H. Redlich: The Grignard Reagent from 2-Bromomethyl-1,3-dioxolane, An Efficient d2-Reagent: Synthesis of Branched Chain Carbohydrate Derivatives , Synthesis, 1996, 8, 1002-1006, doi: 10.1055 / s -1996-4321 .
  • R. Bextermöller, H. Redlich, K. Schnieders, S. Thormählen, R. Fröhlich: Perhydroxylated 1,7-Dioxaspiro [5.5] undecane (“Spirosugar”): Synthesis, Stereochemistry and Structure , Angew. Chem., 1998, 110, pp. 2612-2616, doi: 10.1002 / (SICI) 1521-3757 .
  • P. Arndt, R. Gerdes, S. Huschens, J. Pyplo-Schnieders, H. Redlich: Preparation of cellulose oligomers from cellulose triacetate (standard procedure) , Cellulose 12 317-326, 2005, doi: 10.1007 / s10570-004 .
  • Peter Maier, Hartmut Redlich, Jessica Richter: High enantio- and diastereoselective induction of BINOL- and TADDOL-modified vinyloxy ethoxides in CC coupling reactions with aldehydes , Tetrahedron: Asymmetry 16 (2005) 3848-3852, doi: 10.1016 / j.tetasy. 2005.10.001 .
  • Yue-Lei Chen, Robin Leguijt, Hartmut Redlich: Propane-1,3-diyl Dithioacetals of Carbohydrates; Part 7: Preparation of Aminocyclitols and Iminosugars by Intramolecular Cyclizations of D-Glucosamine Propane-1,3-diyl Dithioacetal Derivatives , Synthesis 2006, 2242-2250, doi: 10.1055 / s-2006-942430 .
  • Yue-Lei Chen, Hartmut Redlich, Klaus Bergander, Roland Fröhlich: D-Glucosamine Trimethylene Dithioacetal Derivatives: Formation of Six- and Seven-Membered Ring Amino Carbasugars. Synthesis of (-) - Calystegine B3, Organic & Biomolecular Chemistry 2007, 3330-3339, doi: 10.1039 / B711112F .
  • Hartmut Redlich, Jochen Lehmann: Carbohydrates. Chemistry and Biology , 2nd edition, Wiley-VCH 1996, ISBN 978-3-13532902-4 .

Web links

Individual evidence

  1. ↑ Biographical data and list of publications up to 1990 after entry in the professorial catalog of the University of Hamburg.
personal data
SURNAME Honest, Hartmut
ALTERNATIVE NAMES Redlich, Hartmut G.
BRIEF DESCRIPTION German chemist (organic chemistry)
DATE OF BIRTH September 19, 1943
PLACE OF BIRTH Wreschen