Hermann Esterbauer

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Hermann Esterbauer (born July 30, 1936 in Ach (Upper Austria) ; † January 7, 1997 in Graz ) was an Austrian chemist who particularly distinguished himself in the research of human metabolism and aging processes.

life and work

Hermann Esterbauer studied physical chemistry at the University of Graz and obtained his doctorate there in 1963 with Erwin Schauenstein . He had succeeded in characterizing 4-hydroxynonenal , a substance that is produced during lipid peroxidation (the rancidity of fats) and which is seen as an important pioneer for diseases such as cancer , Alzheimer's and arteriosclerosis . He then completed his habilitation there in 1970.

After research stays in the USA he returned to Graz and from 1990 headed the Institute for Biochemistry at the university. In total, he researched for over 40 years on the topics of free radicals , antioxidants (especially vitamin E and carotenoids ) and fat oxidation. He wrote 370 specialist articles. Through his work, the relationship between oxidative stress, free radicals, and changes in LDL lipoproteins that can lead to atherosclerosis has been widely recognized.

In his honor, a research association announced the "Esterbauer Award" because he had set new standards as one of the most talented biochemists of the 20th century.

Esterbauer was married and had a daughter.

Works (selection)

  • E. Schauenstein, H. Esterbauer, H. Zollner: Aldehydes in biological systems: their natural occurrence and biological activities. Translated by PH Gore. London 1977, ISBN 0-85086-059-8 .
  • H. Esterbauer, G. Striegl, H. Puhl, M. Rotheneder: Continuous monitoring of in vitro oxidation of human low density lipoprotein. In: Free Radic Res Commun. 6 (1), 1989, pp. 67-75.
  • H. Esterbauer, G. Striegl, H. Puhl, S. Oberreither, M. Rotheneder, M. El-Saadani, G. Jurgens: The role of vitamin E and carotenoids in preventing oxidation of low-density lipoproteins. In: Ann. NY Acad. Sci. 570, 1989, pp. 254-267.
  • H. Esterbauer, SP Gieseg, A. Giessauf, O. Ziouzenkova, P. Ramos: Role of natural antioxidants in inhibiting Cu ++ - mediated oxidation of LDL. In: G. Bellomo, G. Finardi, E. Maggi, C. Rice-Evans (Eds.): Free Radicals Lipoprotein Oxidation and Atherosclerosis-Biological and Clinical Aspects. Richelieu Press, 1995, ISBN 0-903840-10-3 , pp. 11-26.
  • A. Giessauf, E. Steiner, H. Esterbauer: Early destruction of tryptophan residues of apolipoprotein B is a vitamin E-independent process during copper-mediated oxidation of LDL. In: Biochim Biophys Acta. Vol. 1256, 1995, pp. 221-232.

literature

  • Gerhild Kastrun: A life in the laboratory. In: unizeit 1/2015, pp. 22-23 ( online ; PDF; 5.78 MN).

Individual evidence

  1. ^ History of the Institute for Chemistry at the University of Graz , accessed on December 29, 2017.
  2. ↑ boch35.kfunigraz.ac.at/ifc-history/pics/esterbauer/unizeit-1-2015.pdf
  3. ↑ Vitamin E and Carotenoids Protect Arteries from Cholesterol Deposits Interview with Hermann Esterbauer on healthy.net accessed on December 29, 2017.
  4. ^ Obituary in the journal Chemistry and Physics of Lipides , accessed December 29, 2017.
  5. ↑ Homepage of the Esterbauer Award , accessed on December 29, 2017.
personal data
SURNAME Esterbauer, Hermann
BRIEF DESCRIPTION Austrian chemist
DATE OF BIRTH July 30, 1936
PLACE OF BIRTH Oh , Upper Austria
DATE OF DEATH January 7, 1997
Place of death Graz