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The hypoplasia (from ancient Greek ὑποπλασία , Neugriechisch υποπλασία , neulateinisch hypoplasia "insufficient cell formation") or numerical atrophy refers to a genetic (congenital or plant-specific) sub development of an organism, organ system, organ, organ part or tissue, which by the reduction in the number, Elementary parts' (cells) of a system (tissue, muscles, etc.). In the broadest sense, this also means the resulting malfunction. The opposite is hyperplasia .

to form

Developmental, pregnancy and age-associated forms of hypoplasia and aplasia are also summarized under the term involution . A strict separation is not always possible in individual cases.

  • The hypoplastic constitution ( status hypoplasticus ) is the congenital underdevelopment and poor performance of various parts of the body, the heart , the aorta , the adrenal glands , the genital organs , usually associated with enlargement of the thymus and hyperplasia of the lymphatic apparatus ( lymphatic constitution , status lymphaticus / thymicolymphaticus ), which probably also includes exudative diathesis .
  • The pulmonary hypoplasia ( hypoplastic arteria pulmonalis ) stands for the number and size reduction of the airways and alveoli .


  • Elsevier, Lingen (Ed.): Medicine. Human. Health. Helmut Lingen Verlag, Cologne 2006.

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Wiktionary: Hypoplasia  - explanations of meanings, word origins, synonyms, translations