John C. Sheehan

John Clark Sheehan (born September 23, 1915 - March 21, 1992 ) was an American chemist and professor of organic chemistry at the Massachusetts Institute of Technology (MIT).

life and work

Sheehan's scientific work mainly deals with the synthesis of penicillin , as well as the synthesis of peptides , other antibiotics , alkaloids and steroids . His work at MIT led to the first total synthesis of the drug. He also synthesized intermediate compounds such as 6-aminopenicillanic acid, which became the basis for various types of synthetic penicillins. In 40 years, Sheehan patented over 30 compounds, including ampicillin , a semi-synthetic penicillin for oral use. Among the members of his working group was the later Nobel Prize winner E. J. Corey .

The American Chemical Society (ACS) honored Sheehan with its ACS Award in Pure Chemistry in 1951 and with its ACS Award for Creative Work in Synthetic Organic Chemistry in 1959 . In 1951 he was elected to the American Academy of Arts and Sciences , in 1957 to the National Academy of Sciences .

Individual evidence

↑ John C. Sheehan, Kenneth R. Henery-Logan: The Totalsynthesis of Penicillin V. In: Journal of the American Chemical Society. 79, 1957, pp. 1262-1263, doi: 10.1021 / ja01562a063 .
↑ John C. Sheehan, Emmett L. Buhle, Elias J. Corey, Gerald D. Laubach, James J. Ryan: THE TOTAL SYNTHESIS OF A 5-PHENYL PENICILLIN: METHYL 5-PHENYL- (2-CARBOMETHOXYETHYL) -PENICILLINATE. In: Journal of the American Chemical Society. 72, 1950, pp. 3828-3829, doi: 10.1021 / ja01164a534 .

personal data
SURNAME	Sheehan, John C.
ALTERNATIVE NAMES	Sheehan, John Clark
BRIEF DESCRIPTION	American chemist and professor of organic chemistry
DATE OF BIRTH	September 23, 1915
DATE OF DEATH	March 21, 1992

[1] John C. Sheehan, Kenneth R. Henery-Logan: The Totalsynthesis of Penicillin V. In: Journal of the American Chemical Society. 79, 1957, pp. 1262-1263, doi: 10.1021 / ja01562a063 .

[2] John C. Sheehan, Emmett L. Buhle, Elias J. Corey, Gerald D. Laubach, James J. Ryan: THE TOTAL SYNTHESIS OF A 5-PHENYL PENICILLIN: METHYL 5-PHENYL- (2-CARBOMETHOXYETHYL) -PENICILLINATE. In: Journal of the American Chemical Society. 72, 1950, pp. 3828-3829, doi: 10.1021 / ja01164a534 .