Karl Heinrich Welte
Karl Heinrich Welte (born August 23, 1942 in Tettnang ) is a German physician and hematologist . He was a professor at the Hannover Medical School and is a senior professor at the University Children's Hospital in Tübingen.
Career
Welte studied medicine at the University of Tübingen and the Free University of Berlin since 1969 and received his doctorate in Tübingen in 1975. He completed his specialist training at the Children's Clinic of the Free University of Berlin and at the University of Frankfurt and was a research associate in the Laboratory for Molecular Hematopoiesis at the Sloan-Kettering Cancer Center in New York City from 1981 to 1985 . From 1985 to 1987 he was assistant professor, senior physician in paediatrics and laboratory manager for cytokine biology. In 1985 he completed his habilitation at the Medical University of Hanover, where he was appointed professor of pediatrics in 1987 and worked as a senior physician in the Department of Pediatric Hematology and Oncology. In 1993 he was appointed professor for special pediatric hematology and oncology and in 1997 head of the department of pediatric hematology and oncology. From 2008 to 2015 he was director of the department of molecular hematopoiesis with a Lower Saxony professorship for molecular hematopoiesis. Welte currently holds a senior professorship for molecular hematopoiesis at the University Children's Hospital Tübingen, Department I, Hemato-Oncology.
From 2003 to 2007 he was dean of research at MHH. From 2001 to 2005 he was a member of the Senate of the MHH and from 2008 to 2015 a member of the University Council of the MHH.
Welte deals with acute leukemia in children, congenital disorders of blood formation and cytokines and their signaling pathways. From 2001 to 2011 he was the spokesman for the DFG Collaborative Research Center 566 (cytokine receptors and cytokine-dependent signaling pathways) and coordinator of the research network of the Federal Ministry of Education and Research for Congenital Blood Disorders .
He is known for the discovery, characterization and purification of G-CSF (1985), the growth factor of granulocytes . It is used as a drug in cancer therapy and stem cell production and thus enabled the extensive replacement of bone marrow transplantation ( stem cell transplantation ). Welte showed that G-CSF was able to alleviate the harmful side effects of chemotherapy drugs in cancer treatment. He also introduced the therapeutic use of G-CSF in patients with congenital disorders of blood formation ( neutropenia ).
Awards
- 1986 Kind-Philipp Prize in leukemia research
- 1989 Science Prize of the Johann Georg Zimmermann Association (awarded by the MHH).
- 1992 Prix Galien de la recherche Pharmaceutique, Brussels, Belgium
- 2000 Award for Excellency in recognition of distinguished contribution to the field of Hematopoiesis, New Yor, USA
- 2004 German Cancer Aid Prize for excellent scientific work in the field of cloning and therapeutic use of growth factors and research into blood stem cells (laudation).
- In 2015 he received the Henry M. Stratton Medal from the American Society of Hematology .
In 2010 he became a member of the Leopoldina and in 2012 an honorary member of the German Society for Hematology and Oncology.
Web links
Individual evidence
- ↑ Welte u. a., Purification and biochemical characterization of human pluripotent hematopoietic colony-stimulating factor. In: Proc. Natl. Acad. Sci. USA, 82, 1985, pp. 1526-1530
- ↑ Member entry by Prof. Dr. Karl Welte (with picture) at the German Academy of Sciences Leopoldina , accessed on July 20, 2016.
| personal data | |
|---|---|
| SURNAME | Welte, Karl Heinrich |
| BRIEF DESCRIPTION | German physician and hematologist |
| DATE OF BIRTH | August 23, 1942 |
| PLACE OF BIRTH | Tettnang |