Kobophenol A
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| General | ||||||||||
| Surname | Kobophenol A | |||||||||
| other names |
5 - [(2 S , 3 R , 4 S , 5 S ) -4 - [(2 S , 3 S ) -3 - [(2 R , 3 R ) -3- (3,5-dihydroxyphenyl) -6 -hydroxy-2- (4-hydroxyphenyl) -2,3-dihydro-1-benzofuran-4-yl] -6-hydroxy-2- (4-hydroxyphenyl) -2,3-dihydro-1-benzofuran-4- yl] -2,5-bis (4-hydroxyphenyl) oxolan-3-yl] benzene-1,3-diol |
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| Molecular formula | C 56 H 44 O 13 | |||||||||
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| properties | ||||||||||
| Molar mass | 924.94 g mol −1 | |||||||||
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| As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . | ||||||||||
Kobophenol a is a stilbene - tetramer . It can be isolated from Chinese pea bush ( Caragana sinica ).
In the acetylcholinesterase it had an inhibitory in effect.
An acid- catalyzed epimerization of Kobophenol A to the Epimer Carasinol B can be carried out in vitro .
Individual evidence
- ↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
- ↑ Shu Na, Zhou Hong, Hu Changqi: Simultaneous Determination of the Contents of Three Stilbene Oligomers in Caragana sinica Collected in Different Seasons Using an Improved HPLC Method . In: Biological and Pharmaceutical Bulletin . tape 29 , no. 4 , 2006, p. 608–612 , doi : 10.1248 / bpb.29.608 (free full text).
- ↑ Sang Hyun Sung, So Young Kang, Ki Yong Lee, Mi Jung Park, Jeong Hun Kim, Jong Hee Park, Young Chul Kim, Jinwoong Kim and Young Choong Kim: (+) - α-Viniferin, a Stilbene Trimer from Caragana chamlague , Inhibits acetylcholinesterase . In: Biological and Pharmaceutical Bulletin . tape 25 , no. 1 , 2002, p. 125-127 , doi : 10.1248 / bpb.25.125 .
- ↑ B. Kejun Cheng, Gaolin Liang, Hu Changqi: Acid-catalyzed Epimerization of kobophenol a to Carasinol B . In: Molecules . tape 13 , no. 4 , 2008, p. 938-942 , doi : 10.3390 / molecules13040938 .