Paraesthesia

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Classification according to ICD-10
R20.2 Paresthesia of the skin
ICD-10 online (WHO version 2019)

A paresthesia ( Greek παραίσθησις, par-aisthesis, "next to pass by"-Awareness) is an abnormal sensation in the coverage area of a skin nerve without apparent adequate physical stimuli. Those affected usually describe it as tingling, “pins and needles”, furiness, numbness, tingling, itching, a feeling of swelling and a sensation of cold or warmth. Paresthesias are probably based on damage to the non- myelinated end branches of sensitive nerve fibers and the resulting spontaneous discharges, but they can also be caused by damage to sensitive tracts of the central nervous system . The sensation of touching the skin (e.g. tested with a feather) can be quite normal in the affected area.

On the other hand, electrifying abnormal sensations (sensitivity disorders) arise from irritation of a nerve trunk. Disorders of the vegetative fibers can manifest as a painful burning sensation ( causalgia ). A diminished sensation when touching the skin, often perceived as numbness by those affected, is called hypoesthesia . A lack of touch is called anesthesia .

Paresthesias can occur as side effects of acute poisoning and - more permanently - also in the case of diabetes or alcohol addiction in the context of polyneuropathies ("multiple nerve diseases").

They can also occur as a side effect of drugs such as venlafaxine , buspirone , buprenorphine , mirtazapine , oxaliplatin , topiramate or paroxetine and other serotonin reuptake inhibitors . They can also be psychogenic as symptoms of a panic attack .

In particular, slight paresthesias can occur for no apparent reason and usually mean nothing.

See also

Individual evidence

  1. Painful hyperexcitability syndrome during oxaliplatin-containing chemotherapy, The pain, 2007 doi: 10.1007 / s00482-007-0552-5