Lyman C. Craig

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Lyman Creighton Craig (born June 12, 1906 in Palmyra (Iowa) , † July 7, 1974 ) was an American chemist.

Craig graduated from Iowa State University , where he received a Bachelor's degree in 1928 and Ralph M. Hixon on the topic in 1931 Insecticidal action in the nitrogen heterocyclics doctorate was. As a post-doctoral student he was at Johns Hopkins University and from 1933 as a research assistant (and assistant professor) for chemical pharmacology at the Rockefeller Institute in New York City. During the Second World War he worked on anti-malarial drugs. In 1949 he became a professor and member of the Rockefeller Institute, where he stayed for the remainder of his career.

During his research on anti-malaria agents (and insulin tests) in the 1930s, he invented the CCD (countercurrent distribution) technique (also known as Craig's apparatus) to break down chemical substances into their components. The substance to be examined is subjected to a sequence of mixing and demixing processes with two solvents which are immiscible with one another and of which one dissolves the heavy components of the substance, the other the lighter ones. The technology was suitable both for analysis and for the pure display of drugs, for example. With their help, he succeeded in the 1940s in analyzing the first antibiotics that his colleague René Dubos found at the Rockefeller Institute (especially thyrocidines). With his methods he also improved dialysis . In 1934 he found Craig's pyridine bromination for the production of 2-bromopyridine from 2-aminopyridine.

In 1950 he and colleagues also described the rotary evaporator for the first time .

He received the Albert Lasker Award for Basic Medical Research (1963), the Kolthoff Medal from the American Pharmaceutical Association, and the Fisher Award for Analytical Chemistry from the American Chemical Society. In 1950 he was elected to the National Academy of Sciences and in 1961 to the American Academy of Arts and Sciences .

literature

  • Entry in Winfried Pötsch, Annelore Fischer, Wolfgang Müller: Lexicon of important chemists, Harri Deutsch 1989

Web links

Individual evidence

  1. ↑ biographical data, publications and Academic pedigree of Lyman C. Craig at academictree.org, accessed on 28 January 2018th
  2. ↑ Derek Lowe, Das Chemiebuch, Librero 2017, p. 362
personal data
SURNAME Craig, Lyman C.
ALTERNATIVE NAMES Craig, Lyman Creighton
BRIEF DESCRIPTION American chemist
DATE OF BIRTH June 12, 1906
PLACE OF BIRTH Palmyra, Iowa
DATE OF DEATH July 7th 1974