MDA-MB-231

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MDA-MB-231 cells are a model cell line ( breast cancer , adenocarcinoma ) used in biomedical research and the like. a. is used in cancer research . They were isolated from a 51 year old female patient with European ancestry.

The cells are aneuploid . The chromosomes N8 and N15 are missing. They express epidermal growth factor ( EGF ) and transforming growth factor alpha ( TGF alpha). MDA-MB-231 cells grow fibroblastoid- elongated and are highly invasive .

proof

  1. ↑ http://www.lgcstandards-atcc.org/Products/All/CRM-HTB-26.aspx#generalinformation
  2. ↑ Satya-Prakash KL, Pathak S, Hsu TC, Olivé M, Cailleau R. Cytogenetic analysis on eight human breast tumor cell lines: high frequencies of 1q, 11q and HeLa-like marker chromosomes . In: Cancer Genet Cytogenet . 1981; 3: 61-73. PMID 7272986 .
  3. ^ Brinkley BR, Beall PT, Wible LJ, Mace ML, Turner DS, Cailleau RM. Variations in cell form and cytoskeleton in human breast carcinoma cells in vitro . In: Cancer Res . 1980; 40: 3118-3129. PMID 7000337 .

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