Maud Menten

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Maud Menten

Maud Leonora Menten (born March 20, 1879 in Port Lambton , Ontario , † July 26, 1960 in Ontario) was a Canadian doctor.

Life

Maud Menten was one of the first women in Canada to complete a medical degree (University of Toronto, BA 1904, MB 1907, MD 1911). Since women were not allowed to do research in Canada at the time, she went first to Chicago and then to Berlin in 1912 , where she worked with Leonor Michaelis and received her doctorate in natural sciences in 1916.

Together with the German biochemist Leonor Michaelis and based on earlier work by Victor Henri, Maud Menten developed a theory of enzyme kinetics that is still called Henri-Michaelis-Menten kinetics today.

She worked in pathology at the University of Pittsburgh (1923–1950), where she made it to full professor, and as a research fellow at the British Columbia Medical Research Institute (1951–1953). She has published on many topics in medicine and biochemistry: bacterial toxins, characterization of fetal and adult hemoglobin , regulation of blood sugar levels, kidney function , and cancer. She developed an azo dye reaction to detect alkaline phosphatase in histochemistry, which is still used today.

Although she suffered from arthritis, she was also recognized as a painter; her pictures have been exhibited in several galleries.

In 1998 she was posthumously inducted into the Canadian Medical Hall of Fame .

Web links

Individual evidence

  1. ^ V. Henri: Theory generale de l'action de quelques diastases. Compt. rend. hebd. Acad. Sci. Paris 135 (1902): 916-919
  2. ↑ L. Michaelis, ML Menten: The kinetics of the invertin effect, Biochem. Line 49 (1913) 333-369.
  3. ↑ Menten, Maud L., and Helen M. Manning. "Relationship of enteritidis-paratyphoid B infections to hyperglycemia in rabbits." J. Infect. Dis. 37.5 (1925): 400-410.
  4. ↑ King, CG, and ML Menten. "The Influence of Vitamin C Level Upon Resistance to Diphtheria Toxin I. Changes in Body Weight and Duration of Life." J. Nutr. 10.2 (1935): 129-140.
  5. ^ Andersch, Marie A., Donald A. Wilson, and Maud L. Menten. "Sedimentation constants and electrophoretic mobilities of adult and fetal carbonylhemoglobin." J. Biol. Chem. 153.1 (1944): 301-305.
  6. ↑ Menten, Maud L., and Helen M. Manning. "Hyperglycemia and hypoglycemia produced by Witte's peptone." J. Biol. Chem. 72.1 (1927): 255-260.
  7. ↑ Menten, ML "Pathological lesions produced in the kidney by small doses of mercuric chloride." J. Med. Res. 43.3 (1922): 315.
  8. ^ Menten, Maud L., and Miles Janouch. "Changes in Alkaline Phosphatase of Kidney Following Renal Damage with Alloxan." Proc. Soc. Exp. Biol. Med. 63.1 (1946): 33-37
  9. ↑ Menten, Maud L., Josephine Junge, and Mary H. Green. "A coupling histochemical azo dye test for alkaline phosphatase in the kidney." J. Biol. Chem. 153.2 (1944): 471-477.
personal data
SURNAME Menten, Maud
ALTERNATIVE NAMES Menten, Maud Leonora
BRIEF DESCRIPTION Canadian medic
DATE OF BIRTH March 20, 1879
PLACE OF BIRTH Port Lambton
DATE OF DEATH July 26, 1960
Place of death Ontario