Neural migration disorder

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Classification according to ICD-10
Q04.8 Other specified congenital malformations of the brain
ICD-10 online (WHO version 2019)

A neuronal migration disorder is a disorder of brain development during embryo or fetogenesis in which the migration ( cell migration ) of neuroblasts from the germinal layers in the germinal matrix zone to their final location in the brain does not occur normally.

This migration begins from the eighth week of pregnancy along radial glial fibers .

The following classification is common:

Depending on the form of the migration disorder, different degrees of epilepsy can occur.

Individual evidence

  1. ↑ Willibald Pschyrembel : Clinical Dictionary , 266th, updated edition, de Gruyter, Berlin 2014, ISBN 978-3-11-033997-0, keyword. migration
  2. ↑ A. Poduri, JJ Volpe: Neuronal Proliferation . In: Volpe's Neurology of the Newborn , 6th ed., 2018, pp. 100–119, ISBN 978-0-323-42876-7
  3. ↑ W. Schuster, D. Färber (editor): Children's radiology. Imaging diagnostics. 2nd edition, p. 478 ff., Springer 1996, Vol. I, ISBN 3-540-60224-0
  4. ↑ a b A. J. Barkovich: Pediatric Neuroimaging. 2nd edition, Raven 1995, pp. 202 ff., ISBN 0-7817-0179-1
  5. ↑ PM Parizel, H. Tanghe, PAM Hofman: Magnetic Resonance Imaging of the Brain. In: P. Reimer, PM Parizel, F.-A. Stichnoth (Editor): Clinical MR Imaging. A practical approach. Springer, 2nd edition 2006, p. 144, ISBN 3-540-31530-6
  6. ↑ NINDS

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