Nina Khanna

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Nina Khanna Gremmelmaier (* 1975 in Basel ) is a Swiss doctor and infectiologist . She is adjunct professor for infectious diseases at the University of Basel and senior physician at the Clinic for Infectious Diseases and Hospital Hygiene at the University Hospital Basel . She is engaged in the research of new therapeutic strategies for severe infections and the like. a. in immunosuppressed patients with virus-specific T-cell therapies and antibiotic resistance ( multi-resistant germs) and combating them with so-called designer cells .

Career

Nina Khanna was born in Basel in 1975 and studied medicine at the Universities of Freiburg and Basel, which she completed in 2001. For her dissertation in 2002 she researched the - at that time - still new HIV therapies. She also received her specialist training in internal medicine , infectious diseases and epidemiology at the University of Basel, and she also worked as an assistant doctor in Baden and Zurich . As a postdoctoral fellow , she carried out research in the Department of Biomedicine at the University of Basel in the field of transplant virology from 2006 to 2008 and in the field of gene and immunotherapy at the University Hospital Würzburg from 2008 to 2010 .

In 2012, Nina Khanna took over as deputy head of the Infection Biology research laboratory at Basel University Hospital, which has been its head since 2013. For her research project on the immune defense of immunosuppressed people against fungal infections , she was funded in 2012 with the Ambizione research grant from the Swiss National Science Foundation.

She is also a research group leader in the Department of Clinical Research and in the Department of Biomedicine at the University of Basel, as well as a senior physician at the Infectious Disease and Hospital Hygiene Clinic at the University Hospital Basel. From 2015 she was in charge of the consultation service and outpatient infectious disease and expanded the collaboration with the clinic for hematology in the field of transplant infectious diseases. In 2015, Nina Khanna initiated the first clinical phase I / II study (Clin Trials ID NCT02007356) for the adoptive transfer of virus-specific T cells after allogeneic stem cell transplantation.

In 2017 she was appointed adjunct professor for infectious diseases at the University of Basel. For her work on the effectiveness of so-called immunomimetic designer cells, which are antibiotic-resistant bacteria - e . B. Staphylococcus aureus - able to detect and destroy in the body, it was awarded the Science Prize of the City of Basel in 2019 .

Nina Khanna is married and has two children.

Publications (selection)

  • Salvage therapy with abacavir, a non-nucleoside reverse transcriptase inhibitor and a protease inhibitor in heavily pretreated HIV-1 infected patients . (Dissertation). Basel 2002.
  • with Nura Schürmann, Pascal Forrer, Olivier Casse, Jiagui Li, Boas Felmy, Anne-Valérie Burgener, Nikolaus Ehrenfeuchter, Wolf-Dietrich Hardt, Mike Recher, Christoph Hess, Astrid Tschan-Plessl, Dirk Bumann: Myeloperoxidase targets oxidative host attacks to Salmonella and prevents collateral tissue damage . In: Nature Microbiology . tape 2 , no. 4 , January 23, 2017, ISSN  2058-5276 , p. 1-9 , doi : 10.1038 / nmicrobiol.2016.268 .
  • with Ying Liu, Peng Bai, Anne-Kathrin Woischnig, Ghislaine Charpin-El Hamri, Haifeng Ye, Marc Folcher, Mingqi Xie, Martin Fussenegger: Immunomimetic Designer Cells Protect Mice from MRSA Infection . In: Cell . tape 174 , no. 2 , July 2018, p. 259–270.e11 , doi : 10.1016 / j.cell.2018.05.039 , PMID 29937224 , PMC 6057273 (free full text).

Web links

Individual evidence

  1. ↑ a b c d Manuela Bernasconi, Dr. Frank Neumann, Dr. Thomas Schnyder: Newly Appointed Professors 2010–2013 Junior Faculty . In: DBM 2011–2013 Department of Biomedicine . Basel 2013, p. 29 ( unibas.ch [PDF]).
  2. ↑ a b c d Basel Science Award for Infectiologist Nina Khanna Gremmelmaier. Retrieved March 25, 2020 .
  3. ↑ a b c Who is new - Promotion to Senior Physician - PD Dr. Nina Khanna Gremmelmaier . In: Competence . No. 6 . ea media, 2017, ISSN  1424-2168 , p. 34 ( competence-hospitalforum.ch [PDF]).
  4. ↑ salvage therapy with abacavir, a non-nucleoside reverse transcriptase inhibitor and a protease inhibitor in heavily pretreated HIV-1 infected patients . Basel 2002.
  5. ↑ Ambizione: List of grant recipients. In: snf.ch. Swiss National Science Foundation, p. 37 , accessed on March 25, 2020 .
  6. ↑ "Creative mind for research" Interview with PD Dr. Nina Khanna, senior physician in infectious diseases and hospital hygiene . In: DKFORUM The magazine of the Department of Clinical Research . Basel 2015, p. 8–9 ( unispital-basel.ch [PDF]).
  7. ↑ with Ying Liu, Peng Bai, Anne-Kathrin Woischnig, Ghislaine Charpin-El Hamri, Haifeng Ye, Marc Folcher, Mingqi Xie, Martin Fussenegger: Immunomimetic Designer Cells Protect Mice from MRSA Infection . In: Cell . tape 174 , no. 2 , July 2018, p. 259–270.e11 , doi : 10.1016 / j.cell.2018.05.039 , PMID 29937224 , PMC 6057273 (free full text).
personal data
SURNAME Khanna, Nina
ALTERNATIVE NAMES Khanna Gremmelmaier, Nina
BRIEF DESCRIPTION Swiss physician and infectiologist
DATE OF BIRTH 1975
PLACE OF BIRTH Basel