Pacchionic Granulation

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The Pacchionian granulations are small button-like (avascular) Aussackungen the arachnoid membrane (Arachnoidea) through the outermost meninges (Dura mater) into the venous sinuses . They are used to absorb the cerebral fluid (liquor) .

Synonyms are: arachnoid villi; Arachnoid granulations; Latin Granulationes arachnoideales; Foveolae granulares

The name refers to the first description by Antonio Pacchioni in 1705.

These granulations are predominantly found in the frontal area of ​​the drainage area of ​​the superior sagittal sinus ; if they are of the appropriate size, they can form bony thinning zones , the foveolae granulares . They arise from the age of 12.

They are found in at least 2 out of 3 people on magnetic resonance imaging .

These granulations are important in medical imaging for differentiating from sinus thrombosis , but also from possible extradural masses.

Pacchionic granulations can also be detected in birds .


  • H. Park, GY Lim, TH Eom: Giant arachnoid granulation in a child with benign intracranial hypertension: an unusual case. In: Child's nervous system: ChNS: official journal of the International Society for Pediatric Neurosurgery. Volume 34, Number 12, December 2018, pp. 2525-2527, doi: 10.1007 / s00381-018-3898-3 , PMID 30019113 .
  • E. Ayaz, B. Atalay, B. Baysal, S. Senturk, A. Aslan: Giant arachnoid granulation mimicking dural sinus thrombosis. In: Northern clinics of Istanbul. Volume 4, number 2, 2017, pp. 185–187, doi: 10.14744 / nci.2017.93063 , PMID 28971178 , PMC 5613268 (free full text).

Individual evidence

  1. a b Entry on Granulationes arachnoideales in Flexikon , a Wiki of the DocCheck company
  2. ^ Willibald Pschyrembel : Clinical Dictionary , 266th, updated edition, de Gruyter, Berlin 2014, ISBN 978-3-11-033997-0
  3. Who named it
  4. Dissertatio epistolaris de glandulis conglobatis durae Meningis humanae, indeque ortis lymphaticis ad piam Meningem productis. Rome 1705
  5. W. Schuster, D. Färber (editor): Children's radiology. Imaging diagnostics. Vol. 1, p. 391, Springer 1996, ISBN 3-540-60224-0 .
  6. a b Radiopaedia
  7. Differential diagnosis of sinus vein thrombosis
  8. Hannes Rabe, Inaugural Dissertation 2003

Web links