Persistent pupillary membrane

Classification according to ICD-10
H21.4	Pupillary membranes
ICD-10 online (WHO version 2019)

Persistent pupillary membrane

The persistent pupillary membrane , Latin for membrana pupillaris persistens , is a common congenital disease with persistence of a membrane from the embryonic development on the pupil . After the birth, remnants of the fetal pupil remain as a network of fine threads.

The first description comes from 1957 by JR Cassady and A. Light.

Spread and cause

Rudimentary parts of the pupillary membrane can be detected in 95% of newborns. The cause is not known.

The persistence of the pupil membrane also occurs in Gorlin-Chaudhry-Moss syndrome .

Clinical manifestations

Impairment of vision is rare.

diagnosis

The diagnosis results from the ophthalmological examination , also with the slit lamp .

therapy

Treatment is performed surgically if necessary .

In animals

The disease also occurs in veterinary medicine , especially in domestic dogs and cats. It is probably a hereditary disorder, even if the exact inheritance is unknown. There is a racial predisposition for Basenjis , but a familial appearance is also observed in other breeds. It is characterized by incomplete regression of the anterior part of the tunica vasculosa lentis, a fetal vascular network of the lens in the anterior chamber of the eye, which is fed by the hyaloid artery .

literature

• * WB Trattler, P. Keizer, NJ Friedman: Review of ophthalmology. 3rd edition Ed. Elsevier Inc; 2017. pp. 105–278. ISBN 978-0-323-39056-9
• M. Gavriş, I. Horge, E. Avram, R. Belicioiu, IA Olteanu, H. Kedves: Persistent Pupillary Membrane Or Accessory Iris Membrane ?. In: Romanian journal of ophthalmology. Volume 59, number 3, 2015 Jul-Sep, pp. 184-187, PMID 26978889 , PMC 5712966 (free full text).
• SM Lee, YS Yu: Outcome of hyperplastic persistent pupillary membrane. In: Journal of pediatric ophthalmology and strabismus. Volume 41, Number 3, 2004 May-Jun, pp. 163-171, PMID 15206602 (Review).

Individual evidence

1. ↑ Pupillary Membrane, Persistence Of.  In: Online Mendelian Inheritance in Man . (English)
2. ^ Willibald Pschyrembel : Clinical Dictionary , 266th, updated edition, de Gruyter, Berlin 2014, ISBN 978-3-11-033997-0
3. ↑ BJ Burton, GG Adams: Persistent pupillary membranes. In: The British journal of ophthalmology. Volume 82, Number 6, June 1998, pp. 711-712, doi: 10.1136 / bjo.82.6.709b , PMID 9797680 , PMC 1722637 (free full text).
4. ^ JR Cassady, A. Light: Familial persistent pupillary membranes. In: AMA archives of ophthalmology. Volume 58, Number 3, September 1957, pp. 438-448, doi: 10.1001 / archopht.1957.00940010450021 , PMID 13457538 .
5. ↑ ^{a b} P. Meier, U. Gütz, P. Wiedemann: Hyperplastic Persistent Pupillary Membrane - Surgical Procedure. In: Clinical monthly sheets for ophthalmology. Volume 214, Number 4, April 1999, pp. 255-257, doi: 10.1055 / s-2008-1034784 , PMID 10407808 .
6. ↑ Bernfried Leiber (founder): The clinical syndromes. Syndromes, sequences and symptom complexes . Ed .: G. Burg, J. Kunze, D. Pongratz, PG Scheurlen, A. Schinzel, J. Spranger. 7., completely reworked. Edition. tape 2 : symptoms . Urban & Schwarzenberg, Munich et al. 1990, ISBN 3-541-01727-9 .
7. ↑ J. Marolt, M. Peitel, I. Somek: [Persistent pupillary membrane in the dog]. In: DTW. German veterinary weekly. Volume 80, Number 12, June 1973, p. 281, PMID 4578373 .
8. ↑ KN Gelatt (Ed.): Veterinary Ophthalmology (3rd edition). Lippincott, Williams & Wilkins. 1999 ISBN 0-683-30076-8 .

This article is about a health issue. It is not used for self-diagnosis and does not replace a diagnosis by a doctor. Please note the information on health issues !