Roel Nuts
Roeland "Roel" Nusse (born June 9, 1950 in Amsterdam ) is a Dutch - American molecular biologist and professor at Stanford University . He was instrumental in the discovery of the Wnt signaling pathway .
Nusse studied biology at the University of Amsterdam , where he also received his doctorate with a dissertation on the mouse mammary tumor virus . As a post-doctoral student , he discovered the Wnt1 gene with Harold Varmus at the University of California in San Francisco in 1982 . He then continued to investigate the Wnt signaling pathway at the Dutch Cancer Research Institute. From 1990 he was at the Laboratory for Developmental Biology in Stanford. There he is researching, among other things, the role of Wnt in stem cell development and tissue regeneration. He is also a researcher at the Howard Hughes Medical Institute .
In 2000 he received the Peter Debye Prize from Maastricht University. He is a corresponding member of the Royal Dutch Academy of Sciences (1997), a member of the National Academy of Sciences (2010), the American Academy of Arts and Sciences (2001) and the European Molecular Biology Organization (1988).
For 2017 he received the Breakthrough Prize in Life Sciences , for 2020 a Canada Gairdner International Award .
Fonts
- Roel Nusse, Harold Varmus: Three decades of Wnts: A personal perspective on how a scientific field developed , The EMBO Journal, Volume 31, 2012, pp. 2670-2684
- Nusse, Varmus: Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome , Cell, Volume 31, 1982, pp. 99-109, PMID 6297757
- with CY Logan: The Wnt signaling pathway in development and disease , Annu. Rev. Cell Dev. Biology, Vol. 20, 2004, pp. 781-810.
Web links
| personal data | |
|---|---|
| SURNAME | Nuts, Roel |
| ALTERNATIVE NAMES | Nusse, Roeland (full name) |
| BRIEF DESCRIPTION | Dutch molecular biologist and professor at Stanford University |
| DATE OF BIRTH | June 9, 1950 |
| PLACE OF BIRTH | Amsterdam |