TRITC

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Structural formula
Structure of TRITC
General
Surname TRITC
other names

5 (6) tetramethylrhodamine isothiocyanate

Molecular formula C 25 H 21 N 3 O 3 S
Brief description

Solid

External identifiers / databases
CAS number 95197-95-8
EC number 635-450-2
ECHA InfoCard 100.163.338
PubChem 4123009
ChemSpider 3336208
Wikidata Q27902944
properties
Molar mass 443.52 g mol −1
Physical state

firmly

solubility

soluble in DMSO or methanol

safety instructions
GHS labeling of hazardous substances
07 - Warning 08 - Dangerous to health

danger

H and P phrases H: 334-315-319-335
P: 285-261-280-305 + 351 + 338-304 + 340-342 + 311-362-312-405-501
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

TRITC is a coupling reagent from the group of isothiocyanates of tetramethylrhodamine . 5 (6) -TRITC is used as an orange dye for fluorescent labeling of proteins and nucleic acids . In a FRET , TRITC often serves as a fluorescence acceptor.

Individual evidence

  1. a b c d e data sheet 5 (6) -Tetramethylrhodamine isothiocyanate from AlfaAesar, accessed on October 22, 2016 ( PDF )(JavaScript required) .
  2. Greg T. Hermanson: Bioconjugate Techniques. Academic Press, 2013, ISBN 978-0-12-382240-6 , p. 409.
  3. A. Pedone, J. Bloino, S. Monti, G. Prampolini, V. Barone: Absorption and emission UV-Vis spectra of the TRITC fluorophore molecule in solution: a quantum mechanical study. In: Physical Chemistry Chemical Physics . Volume 12, Number 4, January 2010, pp. 1000-1006, doi: 10.1039 / b920255b , PMID 20066385 .