Thermus thermophilus

T. thermophilus
Systematics
Domain : Bacteria (bacteria) Department : Deinococcus Thermus Class : Deinococci Order : Thermales Genre : Thermus Type : T. thermophilus
Scientific name
' Thermus thermophilus'
(ex Oshima and Imahori, 1974) Manaia et al. , 1995

Thermus thermophilus is a gram negative eubacterium and is used in many biotechnological processes. Optimal growth is between 49 and 72 ° C, so the bacterium is very thermophilic . Thermus thermophilus was found in hot springs in Japan and is divided into several subtypes. The HB8 and HB27 subtypes, the genome of which was deciphered in 2004, are themost common ones.

A thermostable polymerase (Tth) relevant for the polymerase chain reaction is obtained from Thermus thermophilus . It catalyzes with optimal activity at 70 to 80 ° C. The enzyme needs divalent ions.

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1. ↑ Henne, A. et al. (2004): The genome sequence of the extreme thermophile Thermus thermophilus . In: Nat Biotechnol . 22 (5); 547-53, PMID 15064768 .

Web links

• Thermus thermophilus HB27 genome page (English).
• Thermus thermophilus HB8 genome page (English).
• Structural-biological whole cell project of Thermus thermophilus HB8 (engl.)