Ulf Pindur

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Ulf Pindur

Ulf Pindur (born January 18, 1943 in Bad Darkau ) is a German pharmacist and food chemist . His field of work was the synthesis and analysis of new drugs with gene-selective binding against cancer .

Life and research

Pindur studied pharmacy and food chemistry at the University of Marburg . There he was promoted to Dr. rer. nat. doctorate and in 1980 in chemistry Pharmaceutical / Medicinal Chemistry on heterocycles of pyrazole, pyrrole and indole series habilitation . In 1980 he became professor for pharmaceutical chemistry / medicinal chemistry at the University of Würzburg . Since 1985 he has been Professor of Pharmaceutical Chemistry / Medicinal Chemistry at the University of Mainz . For many years he was head of the pharmacy institute and chairman of the central committee of the mathematical and natural science departments at the University of Mainz. From 1995 to 2002 he was appointed expert reviewer for the German Research Foundation in Bonn.

Pindur's research areas were drug reactivity, heterocycle chemistry and mainly the development of new peptidomimetics (peptide mimics) as sequence-selective DNA ligands. The presentation of new cancer therapeutics with promising properties was therefore the focus of the research. In addition to organic synthesis and in silico processes, biological and biophysical methods were used. The research results were documented in over 260 publications.

For a total of 30 years he was chairman of the university pharmacy state examination at the universities of Würzburg and Mainz.

Cultural engagement

In addition, Pindur made an appearance with self-produced videos on local cultural monuments of history, including monasteries and cultural landscapes, which were made available free of charge. In addition, science films on medical chemistry are produced.

Awards

  • Science award from the Boehringer Ingelheim Foundation
  • Member of the Advisory Board of the international journals Current Medicinal Chemistry
  • Current Medicinal Chemistry-Anticancer Agents and Medicinal Chemistry-reviews-online.

Selected publications

  • Ulf Pindur, Rainer Deschner: First Electrophilic Substitution of (-) Agroclavine, Indoramine, Phenothiazine, Chlorpromazine, Iminodibenzyl, Imipramine and Phenazone with Triethyl Orthoformate as an a1-Synthon . In: Archives of Pharmacy . Volume 323, 1990, pp. 439-442.
  • Ulf Pindur, Eugenia Gonzalez, Dieter Schollmeyer: New Diels-Alder Reactions of 3-Vinylindoles with Aryne: a Selective Access to Functionalized [a] anellated Carbazoles . In: J. Chem. Soc. Perkin. Trans. I, 1996, pp. 1767-1772.
  • Ulf Pindur, Alparslan Aygün: A New and Effective Method to Carbazoquinozin C and related Carbazol-3,4-quinones as biological Antioxidants: Key Reactions of 2-Vinyindoles with Oxalyl Chloride . In: Synlett . 2000, pp. 1757-1761.
  • Ulf Pindur, Thomas Lemster: Design, Synthesis an Biological / Biophysical Evaluation of new Oligopyrroles carboxamides, Biscarbazoles, Oxocarbazoles and Benzo [a] carbazoles. Antitumor and Antioxidant Compounds . In: Rec. Res. Devel. In Organic and Bioorganic Chemistry . Volume 5, 2002, pp. 99-115.
  • M.-H. David-Cordonnier, M.-P. Hildebrand, B. Baldeyrou, A. Lansiaux, C. Keuser, K. Benzschawel, T. Lemster, U. Pindur: Design, Synthesis and Biological Evaluation of New Oligopyrrole Carboxamides linked with Tricyclic DNA-Intercalators as potential DNA-Ligands or Topoisomerase Inhibitors . In: Eur J Med Chem . Volume 42, 2007, pp. 752-771.

literature

  • Who's Who, name texts of celebrities from politics, business and culture . IBP, Berlin-Montreal-Singapore-Vienna 2002
  • Kürschner's German Scholars Calendar . KC Sauer, Munich 2000

Web links

personal data
SURNAME Pindur, Ulf
BRIEF DESCRIPTION German university professor
DATE OF BIRTH January 18, 1943
PLACE OF BIRTH Bad Darkau