Uroporphyrinogens

Uroporphyrinogen I.

Uroporphyrinogen III

Uroporphyrinogens are a group of chemical compounds . They occur naturally as intermediate stages in the biosynthesis of porphyrins , such as the blood pigment heme or cyanocobalamin (vitamin B ₁₂ ). The porphyrinogens include the cyclic tetrapyrroles with four propionic acid ( P ) and four acetic acid ( A ) groups.

Types

There are four compositions of the A and P groups, of which only uroporphyrinogen I (AP-AP-AP-AP) and, as the most common form, uroporphyrinogen III (AP-AP-AP-PA) are identified in nature were. The latter is produced from the linear tetrapyrrole hydroxymethylbilane by the enzyme uroporphyrinogen III synthase .

Individual evidence

1. ↑ Gerhard Habermehl: Naturstoffchemie: an introduction . Springer DE, 2008, ISBN 978-3-540-73733-9 , pp. 514 ( limited preview in Google Book search).
2. ↑ Gerhard Habermehl: Naturstoffchemie: an introduction . Springer DE, 2008, ISBN 978-3-540-73733-9 , pp. 559 ( limited preview in Google Book search).