N -Arachidonoyl-4-hydroxy-2-methylaniline

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Structural formula
Structure of VDM-11
General
Surname N -Arachidonoyl-4-hydroxy-2-methylaniline
other names

VDM-11

Molecular formula C 27 H 39 NO 2
Brief description

yellow liquid

External identifiers / databases
CAS number 313998-81-1
EC number 631-144-8
ECHA InfoCard 100.159.410
PubChem 9887748
Wikidata Q6624893
properties
Molar mass 409.61 g · mol -1
Physical state

liquid

solubility

Soluble in ethanol and DMSO

safety instructions
GHS labeling of hazardous substances
07 - Warning 08 - Dangerous to health

Caution

H and P phrases H: 302-312-332-334
P: 261-280-342 + 311
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

N -Arachidonoyl-4-hydroxy-2-methylaniline (also known as VDM-11 ) is an endocannabinoid reuptake inhibitor that serves as a potent and selective inhibitor of the anandamide membrane transporter (AMT) and has negligible agonistic activity on the TRPV1 receptor and has a very weak effect on the CB1 and CB2 receptors .

It is photosensitive and is stored in inert gases such as argon at temperatures below −20  ° C.

Individual evidence

  1. ↑ a b c d data sheet VDM 11 at Sigma-Aldrich , accessed on February 29, 2016 ( PDF ).
  2. ↑ a b VDM 11 Cat. No. 1392. Tocris Bioscience, accessed February 29, 2016 .