Virginia Man-Yee Lee
Virginia Man-Yee Lee (* 1945 in Chongqing ) is a Chinese-American neuropathologist and immunobiologist.
Virginia M.-Y. Lee grew up in Hong Kong and has a degree in music (piano) from the Royal Academy of Music (1964, she was in London since 1962) and studied chemistry at the University of London with a bachelor’s degree in 1967 and biochemistry with a master’s degree. Graduated in 1968. She received her PhD in biochemistry in 1973 from the University of California, San Francisco , and was a post-doctoral student at the Rudolf Magnus Institute of Pharmacology at the University of Utrecht and from 1974 to 1979 in the neuropathology department of the Children's Hospital Medical Center and Harvard Medical School in Boston. She also holds an MBA from the Wharton School (1984). In 1979/80 she worked for the pharmaceutical company Smith-Kline & French in Philadelphia and from 1981 she was Assistant Professor (research) at the University of Pennsylvania Perelman School of Medicine, from 1986 Associate Professor (research) and from 1990 as a research professor and from 1993 as a professor of pathology and laboratory medicine. She has been the John H. Ware 3rd Endowed Professor in Alzheimer's Research and Director of the Center for Neurodegenerative Disease Research and Co-Director of the Marian S. Ware Alzheimer's Drug Discovery Program since 1999 .
She deals with neurodegenerative diseases such as Alzheimer's disease , Parkinson's disease , ALS , frontotemporal lobe degeneration (FTLD), tauopathies , synucleinopathy , TDP 43 proteinopathy and involved proteins such as tau protein , synuclein and TDP-43, which she discovered . She found that the accumulation of proteins such as tau, alpha-synuclein and TDP-43 is a common characteristic of many neurodegenerative diseases, especially in old age. She also examines the neural cytoskeleton.
In 1997 she received the Rita Hayworth Award for her Alzheimer's research and in 2009 a prize for her life's work in Alzheimer's research from the Alzheimer Foundation. In 2012 she received the Pasarow Award in Neuropsychiatry and the John Scott Award . For 2020 she is one of the winners for the Breakthrough Prize in Life Sciences for the discovery of TDP 43. She is a member of the American Academy of Arts and Sciences (2013) and the Institute of Medicine (from 2006).
She has been married to John Trojanowski since 1979 , with whom she also collaborates scientifically and is also involved in scientific disputes, which was also reflected in a chapter in the book The Hidden Brain (2010) by Shankar Vedantam.
Web links
- Homepage, University of Pennsylvania
- Rajendrani Mukhopadhyay: Virginia Lee, notes on a career , ASBMB Today
Individual evidence
- ^ Entry in American Men and Women of Science , Thomson Gale 2004
- ↑ Book of Members 1780 – present, Chapter L. (PDF; 1.1 MB) In: American Academy of Arts and Sciences (amacad.org). Accessed September 7, 2019 .
| personal data | |
|---|---|
| SURNAME | Lee, Virginia Man-Yee |
| BRIEF DESCRIPTION | American neuropathologist and immunobiologist |
| DATE OF BIRTH | 1945 |
| PLACE OF BIRTH | Chongqing |