Xylose isomerase

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Xylose isomerase
other names

D-acidic-ketolysoisomerase, glucose isomerase

Existing structure data : PDB  1GW9 , PDB  1MNZ , PDB  1O1H

Mass / length primary structure 388 amino acids , 43,227 Da
Secondary to quaternary structure Homotetramer
Identifier
External IDs
Enzyme classification
EC, category 5.3.1.5

Xylose isomerase is an enzyme from the bacterium Streptomyces rubiginosus . It is used industrially for the production of isoglucose from glucose syrup . Xylose isomerase is also produced by various other types of bacteria.

properties

The xylose isomerase is involved in the breakdown of D- xylose in S. rubiginosus . After translation , the formyl methionine is split off at the N terminus .

The catalyzed reaction of xylose isomerase:

D-xylose (a pyranose ) D- xylulose (a furanose )

Because it also converts glucose to fructose , it is used in the production of isoglucose, mostly in the production of HFCS .

Web links

Individual evidence

  1. ↑ Andreas Liese: Industrial Biotransformations. John Wiley & Sons, 2008, ISBN 978-3-527-61417-2 , p. 388.
  2. ↑ a b xylA - Xylose isomerase - Streptomyces rubiginosus - xylA gene & protein. In: uniprot.org. June 20, 2018, accessed June 29, 2018 .