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Revision as of 19:39, 12 April 2021

Mark Siddall
File:SiddallZambia.jpg
Siddall on an expedition in Zambia.
Born (1966-11-22) November 22, 1966 (age 57)
Toronto, Canada
Children2
Scientific career
Fields

Mark E. Siddall is a Canadian[1] invertebrate zoologist and infectious disease expert.[2]

Siddall's research has focused on the diversity and evolutionary biology of a wide range of parasites, from single-celled microbes to leeches. He has led expeditions throughout the world, most recently including South Sudan, Cambodia, the Lower Amazon of Brazil, and Madagascar. His work ranges from sequencing the whole genome of bed bugs uncovering hemotoxic venom compounds in blood feeding animals, to leveraging iDNA as a measure of endangered animal diversity in protected tropical forests.[3] In addition to over 160 peer reviewed publications,[4] he is author of the whimsical[3] book “Poison: Sinister species with deadly consequences”.[5] Siddall is a committed science communicator making frequent public program appearances, at venues around New York City and more widely; even garnering recognition from the Entertainment Exchange of the National Academy of Sciences.[3] He has curated of the Irma and Paul Milstein Family Hall of Ocean Life and other exhibitions including The Power of Poison, Life at the Limits: Stories of Amazing Species, Picturing Science, Undersea Oasis and Countdown to Zero: Defeating Disease[3] in collaboration with President Jimmy Carter. Siddall received his Ph.D. from the University of Toronto in 1994, is a recipient of the Henry Baldwin Ward Medal from the American Society of Parasitologists and is a Fellow of The Explorers Club.[3]

Education

Siddall completed a Bachelor of Science in Microbiology and Immunology, a Masters [6] and PhD in Parasitology[7] under the supervision of Sherwin S. Desser at the University of Toronto in 1988, 1991 and 1994, respectively.[8]

Career

After completing his PhD in 1994, Siddall started a postdoc at the Virginia Institute of Marine Science under the supervision of Eugene Burreson. Though Burreson is a noted marine leech systematist, their collaborations concerned protozoon parasites of oysters including "dermo" (Perkinsus marinus) and "MSX" (Haplosporidium nelsoni and other economically important species in the parasitic phylum Haplosporidia.[9] That research demonstrated that MSX began wiping out the Atlantic oysters in the Chesapeake Bay and elsewhere as a result of the introduction of oysters from Asia.[10] His phylogenetic work showing that Perkinsus marinus is a dinoflagellate[11][12] overturned environmental monitoring methods.[13] At The College of William and Mary Siddall began working on a solution to the long-standing problem of correlating ordinal fossil age (stratigraphic) data to bifurcating tree structures in a manner that was not biased by the shape of the tree.[14][15]

Subsequently, Siddall was a Michigan Society of Fellow from 1996 - 1999[16] at the University of Michigan where he worked closely with Arnold Kluge taking on Jessica Light (now faculty at TAMU) as an undergraduate intern. It was as a Michigan Society Fellow that Siddall that Siddall drew heavily on Karl Popper in formulating an urgent critique of maximum likelihood for the inference of phylogenies[17]. It was also during this period in which Siddall contributed to understanding the coevolutionary history of HIV coevolution[18][19].

Siddall was hired at the American Museum of Natural History in July, 1999[1] and served there as a curator until September, 2020. The first researcher he sponsored in his new role was Susan Perkins in order to allow her to achieve a major contribution to understanding the evolution of malaria parasites.[20] Siddall took her on as his first postdoctoral scholar, supported her hire at the University of Colorado, and encouraged her to apply to the microbiology curatorship at the American Museum of Natural History.

Siddall took over stewardship of the museum's summer Research Experiences for Undergraduates Program in 2000 shepherding it through two decades of uninterrupted National Science Foundation grant funding. The program saw the mentorship of more than 200 undergraduates in biodiversity and evolutionary biology research, 52% under grant DBI-1358465 were recruited from academic institutions where research opportunities in STEM are limited.[21] Siddall is known for matching the representation of women (71%) and minorities (31%) in the program to the proportions of those applying.[21] Fully 39% of the interns he admitted into the program are in tenure track faculty positions among whom women represent 67%.[21] His former interns include Lauren Esposito at the California Academy of Sciences and Anna J. Phillips at the Smithsonian Institution.

The American Museum of Natural History let him go in September 2020 after the law firm it retained to represent its interests, Kaplan Hecker & Fink[22] led by Roberta Kaplan (co-founder of the Time's Up Legal Defense Fund[23]) provided the museum with a determination that he had sexually harassed a graduate student as conclusion to a complaint that did not include that charge. The choice of Kaplan Hecker & Fink deviated from all prior investigations of sexual harassment at the American Museum of Natural History handled by T&M Protection and which did not result in terminations.[24][25] As part of the investigation, which occurred when the American Museum of Natural History was seeking to fill a $120 million budget gap,[26] Siddall was cited for violating a museum policy that prohibits sexual relationships between staff and mentees under their academic supervision.[27] Siddall denied anything of a sexual nature took place and denied that the graduate student was ever under his supervision.[28] In support of Siddall's claim, the AMNH's own graduate school roster from that time period does not indicate any student being under his academic supervision either in the museum's own Richard Gilder Graduate School Comparative Biology program or in its Collaborative Program at partnering universities.[29]

Worried about data-fabrication in a paper they were coauthoring, Siddall asked to remove his name from the paper on 22 May 2020.[22][28] Within days of that request[28] the graduate student filed a sexual assault complaint that was not upheld in the investigation.[22] Siddall also publicly disagreed with the lesser harassment findings that led to his dismissal, however, he chose to not appeal the decision to protect his family from legal costs as his son was entering remote Kindergarten, his daughter was applying to colleges and his wife was trying to complete her own graduate degree.[22][28] The American Museum of Natural History responded with termination, even though there was no record of a prior sexual harassment complaint against Siddall,[28] thus putting Siddall out of work, and ineligible for unemployment benefits[30] in the middle of a global pandemic.

Communicating Science

Siddall has presented his passion for parasites and biological sciences for a wide range of audiences including TED[31], The Pebble Beach Authors and Ideas Festival[32], Play Fair, Comic Con[33], Idea City[34], the Northeastern Society of Scientific Skeptics, the Humanist Society[35], as well as multiple appearances at the EG Conference[36], The National Academy of Sciences[37][38], The World Science Festival[39][40][41][42], New York's Secret Science Club[43][44] and the Explorers Club[3][45].

He has been invited to participate in in public panel programs with Jimmy Carter and Tom Frieden regarding disease eradication[46], at the Carter Center[47], the Social Good Summit, and the World Economic Forum[48]. He has himself hosted panel programs concerning Big Data[49], and especially disease eradication at the Carter Center[47] and at the World Health Organization[48] while also serving as host and Chair of Public Programs at the Explorers Club[50].

Research

Siddall procured millions of dollars in grant funding for the American Museum of Natural History from the National Science Foundation, the National Institutes of Health, and several private foundations.[51] He has an h-index of 50 having authored 169 peer-reviewed publications that have been cited over 9,000 times.[4] Siddall's expertise covers the biodiversity, detection and disease roles of pathogens and how they inform socioeconomic and ecosystem health.[4] His international field work has covered more than 30 countries across South America, Asia and Africa, mostly in developing countries including the Carter Center's program in South Sudan.[52]

He has actively engaged the transformation of DNA sequencing from the days of reading radioactive traces by-eye to the current next-gen (NGS) frameworks and their myriad applications. At the Institute of Comparative Genomics, Siddall spearheaded the build-out the NGS program at the American Museum of Natural History while pushing for a bioinformatics team as a community resource. He has sequenced whole animal genomes from scratch (i.e., unguided “de novo”) leveraging Illumina, Moleculo, and PacBio for the Bed Bug genome, and most recently 10x Genomics for the whole genome of the Medicinal Leech.[53] His published work includes RNAseq transcriptomics, much of which is tissue-specific (e.g., anticoagulants in salivary gland cells of blood-feeding vectors).[53]

Siddall's research ranges from genome-wide screens of tuberculosis against immune system reporter genes to deep metagenomic assessments of biodiversity and their associated microbiomes.[4] He has innovated on environmental DNA (eDNA/iDNA), metagenomics and high-resolution scientific imaging,[4] much of which was translated for public consumption in the award-winning exhibition (Picturing Science).

He has published extensively on leech systematics.[54][55][56]

Filmography

Year Title Role Notes
2004 John Lydon's MegaBugs Himself Episode: Leeches
2005 Bug Attack Himself
2008 Nova ScienceNow Himself Episode: Kingdom of the Leeches
2009 Finding Leeches in Rwanda Himself
2009 Nova The Secret Life of Scientists Himself Episode 1
2010 Discovery: Nasty by Nature Himself
2011 NatGeo Wild Himself Episode: Invaders
2012 rDigitial Life Himself On the Environment
2015 Shelf Life Himself Episode: Voyage of the Giant Squid
2016 Science Goes to the Movies Himself Episode: Zombies
2017 Science Goes to the Movies Himself Episode: Alien Covenant
2018 Science Goes to the Movies Himself Episode: Alien Parasites How They Changed Humans
2019 Science Goes to the Movies Himself Episode: Super Hero Symbiotes
2020 Science Goes to the Movies Himself Episode: 93 Days and Contagion, Fictional Virus Wars

References

  1. ^ a b "INTRODUCTION OF PRESIDENT MARK E. SIDDALL - ProQuest". search.proquest.com.
  2. ^ "Disease experts reveal their biggest worries about the next pandemic". 2021-03-12.
  3. ^ a b c d e f The Explorers Club (2018-04-30). "Public Lecture Series with Mark Siddall - The Bloodsucker Proxy: Terrestrial Leeches and Revolutionary New Techniques For Genetic Forest Sampling".
  4. ^ a b c d e "Google Scholar Profile for Mark Siddall". Retrieved 2021-03-12.
  5. ^ "Poison: Sinister Species with Deadly Consequences - Mark Siddall - Google Books". Google.com. Retrieved 2021-03-12.
  6. ^ "U of T Magazine | Winter 2014". Issuu.
  7. ^ "Mark Siddall". World Science Festival. Retrieved 2021-03-12.
  8. ^ Siddall, Mark E. (2016). "Presidential Address: Reinvention and Resolve". The Journal of Parasitology. 102 (6): 566–571. doi:10.1645/16-113. JSTOR 44810235. PMID 27626125. S2CID 11802614.
  9. ^ "Google Scholar results for Siddall Burreson Haplosporidia Perkinsus". Retrieved 2021-04-09 – via Scholar.Google.com.
  10. ^ Burreson, E.M. (2004). "A review of recent information on the Haplosporidia, with special reference to Haplosporidium nelsoni (MSX disease)". {{cite journal}}: Cite journal requires |journal= (help)
  11. ^ Reece, K. S.; Siddall, M. E.; Burreson, E. M.; Graves, J. E. (1997-06-XX). "Phylogenetic analysis of Perkinsus based on actin gene sequences". The Journal of Parasitology. 83 (3): 417–423. ISSN 0022-3395. PMID 9194820. {{cite journal}}: Check date values in: |date= (help)
  12. ^ Siddall, M. E.; Reece, K. S.; Graves, J. E.; Burreson, E. M. (1997-08-XX). "'Total evidence' refutes the inclusion of Perkinsus species in the phylum Apicomplexa". Parasitology. 115 ( Pt 2): 165–176. doi:10.1017/s0031182097001157. ISSN 0031-1820. PMID 10190172. {{cite journal}}: Check date values in: |date= (help)
  13. ^ Bushek, David; Dungan, Christopher F.; Lewitus, Alan J. (2002-01-XX). "Serological affinities of the oyster pathogen Perkinsus marinus (Apicomplexa) with some dinoflagellates (Dinophyceae)". The Journal of Eukaryotic Microbiology. 49 (1): 11–16. doi:10.1111/j.1550-7408.2002.tb00333.x. ISSN 1066-5234. PMID 11908893. {{cite journal}}: Check date values in: |date= (help)
  14. ^ "Abstract of Papers. Fifty-Seventh Annual Meeting, Society of Vertebrate Paleontology". 1997 – via Journal of Vertebrate Paleontology. {{cite journal}}: Cite journal requires |journal= (help)
  15. ^ Mark Siddall (1998). "Stratigraphic Fit to Phylogenies: A Proposed Solution" – via Cladistics. {{cite journal}}: Cite journal requires |journal= (help)
  16. ^ "All Events | U-M LSA University of Michigan Herbarium". lsa.umich.edu.
  17. ^ Siddall, Mark E.; Kluge, Arnold G. (1997). "Probabilism and Phylogenetic Inference". Cladistics. 13 (4): 313–336. doi:10.1111/j.1096-0031.1997.tb00322.x. ISSN 1096-0031.
  18. ^ Mindell, David P.; Shultz, Jeffrey W.; Ewald, Paul W. (1995). "The AIDS Pandemic Is New, But Is HIV New?". Systematic Biology. 44 (1): 77–92. doi:10.2307/2413484. ISSN 1063-5157.
  19. ^ Siddall, Mark E. (1997). "The AIDS Pandemic is New, but is HIV Not New?". Cladistics. 13 (3): 267–273. doi:10.1111/j.1096-0031.1997.tb00319.x. ISSN 1096-0031.
  20. ^ Perkins, Susan L.; Schall, JosJ (2002/10). "A MOLECULAR PHYLOGENY OF MALARIAL PARASITES RECOVERED FROM CYTOCHROME b GENE SEQUENCES". Journal of Parasitology. 88 (5): 972–978. doi:10.1645/0022-3395(2002)088[0972:AMPOMP]2.0.CO;2. ISSN 0022-3395. {{cite journal}}: Check date values in: |date= (help)
  21. ^ a b c Siddall, Mark (2019-08-28). "REU SITE: Systematics, Evolution and Conservation for the 21st Century" (PDF).{{cite web}}: CS1 maint: url-status (link)
  22. ^ a b c d Jacobs, Julia (2020-10-02). "Museum Fires Curator Who It Says Sexually Harassed Student Researcher" – via NYTimes.com.
  23. ^ "Time's Up Co-Founder to Represent Media Men List Creator". New York Times. Retrieved 2018-10-16.
  24. ^ Sceincemag.org (2016-02-09). "The sexual misconduct case that has rocked anthropology".
  25. ^ New York Times (2019-07-26). "After Investigation, Neil deGrasse Tyson Will Keep His Job".
  26. ^ Jacobs, Julia (2020-05-06). "Natural History Museum Slashing Staff With Layoffs and Furloughs" – via NYTimes.com.
  27. ^ "Richard Gilder Graduate School Handbook for Students and Faculty on Academic and Conduct Policies and Procedures" (PDF). AMNH.org. Retrieved 2021-02-22.
  28. ^ a b c d e "Response to New York Times Inquiry – September 23, 2020". Internet Archive. Retrieved 2021-02-22.
  29. ^ "Meet Our PhD Students". Internet Archive. Retrieved 2020-03-03.
  30. ^ Nolo.com. "How to Collect Unemployment Benefits in New York". Retrieved 2021-04-09.
  31. ^ "TEDYouth 2014". www.ted.com. Retrieved 2021-04-12.
  32. ^ "In its 10th year, Authors and Ideas Fest still inspiring kids". Monterey Herald. 2017-09-22. Retrieved 2021-04-12.
  33. ^ "2013 programming schedule - movies". doczz.net. Retrieved 2021-04-12.
  34. ^ "Mark Siddall". ideacity. Retrieved 2021-04-12.
  35. ^ "Mark E. Siddall / Bioluminescence: A Survival Tactic – Darwin Day Connecticut". Retrieved 2021-04-12.
  36. ^ "TED Youth Mark Siddall Leech Expert".{{cite web}}: CS1 maint: url-status (link)
  37. ^ "Berggruen Institute". Berggruen Institute. Retrieved 2021-04-12.
  38. ^ "The Science of Sex – Exchange". Retrieved 2021-04-12.
  39. ^ "Cool Jobs: Leech Expert Mark Siddall - Vloggest". vloggest.com. Retrieved 2021-04-12.
  40. ^ "Past Events". World Science Festival. Retrieved 2021-04-12.
  41. ^ "Mark Siddall". World Science Festival. Retrieved 2021-04-12.
  42. ^ "SCIENTIFIC SAILS: Adventure Time with an Evolutionary Biologist Adventurer". World Science Festival. Retrieved 2021-04-12.
  43. ^ "The Secret Science Club". secretscienceclub.blogspot.com. Retrieved 2021-04-12.
  44. ^ Club, Secret Science (2014-10-03). "The Secret Science Club: Secret Science Club (North) presents Invertebrate Zoologist Mark Siddall @ Symphony Space, Tuesday, October 14, 8PM". The Secret Science Club. Retrieved 2021-04-12.
  45. ^ "The Explorers Club -". explorersclub.org. Retrieved 2021-04-12.
  46. ^ Countdown to Zero: Defeating Disease (Jan. 11, 2017), retrieved 2021-04-12
  47. ^ a b "The Carter Center". Retrieved 2021-04-12.
  48. ^ a b "Speaker". Mark Siddall. Retrieved 2021-04-12.
  49. ^ "The Human Face of Big Data".{{cite web}}: CS1 maint: url-status (link)
  50. ^ "The Explorers Club". explorers.org. Retrieved 2021-04-12.
  51. ^ MarkSiddall.net (2021-04-08). "Grants Awarded to Mark Siddall".
  52. ^ MarkSiddall.net (2021-04-08). "Mark Siddall Explorer".
  53. ^ a b MarkSiddall.net (2021-04-08). "Mark Siddall Peer Reviewed Publications".
  54. ^ Siddall, Mark E.; Burreson, Eugene M. (October 1, 1996). "Leeches (Oligochaeta?: Euhirudinea), their phylogeny and the evolution of life-history strategies". Hydrobiologia. 334 (1): 277–285. doi:10.1007/BF00017378. S2CID 21736028 – via Springer Link.
  55. ^ Siddall, Mark E.; Burreson, Eugene M. (February 1, 1998). "Phylogeny of Leeches (Hirudinea) Based on Mitochondrial CytochromecOxidase Subunit I". Molecular Phylogenetics and Evolution. 9 (1): 156–162. doi:10.1006/mpev.1997.0455. PMID 9479704 – via ScienceDirect.
  56. ^ "Download Limit Exceeded". citeseerx.ist.psu.edu.