Zinc transporter ZIP1: Difference between revisions
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'''Zinc transporter ZIP1''' is a [[protein]] that in humans is encoded by the ''SLC39A1'' [[gene]].<ref name="pmid10610721">{{cite journal | author = Lioumi M, Ferguson CA, Sharpe PT, Freeman T, Marenholz I, Mischke D, Heizmann C, Ragoussis J | title = Isolation and characterization of human and mouse ZIRTL, a member of the IRT1 family of transporters, mapping within the epidermal differentiation complex | journal = Genomics | volume = 62 | issue = 2 | pages = 272–80 | |
'''Zinc transporter ZIP1''' is a [[protein]] that in humans is encoded by the ''SLC39A1'' [[gene]].<ref name="pmid10610721">{{cite journal | author = Lioumi M, Ferguson CA, Sharpe PT, Freeman T, Marenholz I, Mischke D, Heizmann C, Ragoussis J | title = Isolation and characterization of human and mouse ZIRTL, a member of the IRT1 family of transporters, mapping within the epidermal differentiation complex | journal = Genomics | volume = 62 | issue = 2 | pages = 272–80 |date=Feb 2000 | pmid = 10610721 | pmc = | doi = 10.1006/geno.1999.5993 }}</ref> |
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<ref name="pmid10681536">{{cite journal | author = Gaither LA, Eide DJ | title = Functional expression of the human hZIP2 zinc transporter | journal = J Biol Chem | volume = 275 | issue = 8 | pages = 5560–4 | |
<ref name="pmid10681536">{{cite journal | author = Gaither LA, Eide DJ | title = Functional expression of the human hZIP2 zinc transporter | journal = J Biol Chem | volume = 275 | issue = 8 | pages = 5560–4 |date=Mar 2000 | pmid = 10681536 | pmc = | doi =10.1074/jbc.275.8.5560 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SLC39A1 solute carrier family 39 (zinc transporter), member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27173| accessdate = }}</ref> |
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The protein ZIP1 is responsible for the active transport of [[zinc]] into [[prostate]] cells. In many [[prostate cancer]]s SLC39A1 is silenced causing prostate cancer cells to be low in zinc.<ref name="pmid16700911">{{cite journal | author = Costello LC, Franklin RB | title = The clinical relevance of the metabolism of prostate cancer; zinc and tumor suppression: connecting the dots | journal = Mol. Cancer | volume = 5 | issue = | pages = 17 | year = 2006 | pmid = 16700911 | pmc = 1481516 | doi = 10.1186/1476-4598-5-17 | url = | issn = }}</ref> |
The protein ZIP1 is responsible for the active transport of [[zinc]] into [[prostate]] cells. In many [[prostate cancer]]s SLC39A1 is silenced causing prostate cancer cells to be low in zinc.<ref name="pmid16700911">{{cite journal | author = Costello LC, Franklin RB | title = The clinical relevance of the metabolism of prostate cancer; zinc and tumor suppression: connecting the dots | journal = Mol. Cancer | volume = 5 | issue = | pages = 17 | year = 2006 | pmid = 16700911 | pmc = 1481516 | doi = 10.1186/1476-4598-5-17 | url = | issn = }}</ref> |
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Revision as of 03:27, 30 January 2014
Template:PBB Zinc transporter ZIP1 is a protein that in humans is encoded by the SLC39A1 gene.[1] [2][3]
The protein ZIP1 is responsible for the active transport of zinc into prostate cells. In many prostate cancers SLC39A1 is silenced causing prostate cancer cells to be low in zinc.[4]
See also
References
- ^ Lioumi M, Ferguson CA, Sharpe PT, Freeman T, Marenholz I, Mischke D, Heizmann C, Ragoussis J (Feb 2000). "Isolation and characterization of human and mouse ZIRTL, a member of the IRT1 family of transporters, mapping within the epidermal differentiation complex". Genomics. 62 (2): 272–80. doi:10.1006/geno.1999.5993. PMID 10610721.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ Gaither LA, Eide DJ (Mar 2000). "Functional expression of the human hZIP2 zinc transporter". J Biol Chem. 275 (8): 5560–4. doi:10.1074/jbc.275.8.5560. PMID 10681536.
{{cite journal}}: CS1 maint: unflagged free DOI (link) - ^ "Entrez Gene: SLC39A1 solute carrier family 39 (zinc transporter), member 1".
- ^ Costello LC, Franklin RB (2006). "The clinical relevance of the metabolism of prostate cancer; zinc and tumor suppression: connecting the dots". Mol. Cancer. 5: 17. doi:10.1186/1476-4598-5-17. PMC 1481516. PMID 16700911.
{{cite journal}}: CS1 maint: unflagged free DOI (link)
Further reading
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