Sodium–hydrogen antiporter 3
Sodium-hydrogen antiporter 3 or Sodium-hydrogen exchanger 3 (NHE3) is an isoform of sodium-hydrogen antiporters. It is found in the nephron of the kidney and is primarily responsible for maintaining the balance of sodium.[1] [2]
Regulation
Protein kinase C stimulates NHE3, while protein kinase A inhibits it. [3]
There is a specific protein functioning as an NHE3 regulator, sodium-hydrogen antiporter 3 regulator 1.
Classification
It is a solute carrier family 9 (sodium/hydrogen exchanger), member 3
Gene
It is encoded by the gene SLC9A3.
References
- ^ VI. Mechanisms of Salt & Water Reabsorption
- ^ "Entrez Gene: SLC9A3 Solute carrier family 9 (sodium/hydrogen exchanger), member 3".
- ^ 852 Walter F., PhD. Boron. Medical Physiology: A Cellular And Molecular Approaoch. Elsevier/Saunders. ISBN 1-4160-2328-3. Page 852
Further reading
External links
- Sodium-Hydrogen+Exchanger at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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