Multidrug and toxin extrusion protein 1
Template:PBB Solute carrier family 47, member 1, also known as SLC47A1, is a protein which in humans is encoded by the SLC47A1 gene.[1][2]
Function
This gene is located within the Smith-Magenis syndrome region on chromosome 17.[1]
SLC47A1 belongs to a MATE (multidrug and toxic compound extrusion) family of transporters that are found in bacteria, archaea and eukaryotes. In human MATE transporters excrete endogenous and exogenous toxic electrolytes through urine and bile.[2]
See also
- MATE protein (Multi antimicrobial extrusion protein or multidrug and toxic compound extrusion protein)
References
- ^ a b "Entrez Gene: FLJ10847 hypothetical protein FLJ10847".
- ^ a b Otsuka M, Matsumoto T, Morimoto R, Arioka S, Omote H, Moriyama Y (2005). "A human transporter protein that mediates the final excretion step for toxic organic cations". Proc. Natl. Acad. Sci. U.S.A. 102 (50): 17923–8. doi:10.1073/pnas.0506483102. PMC 1312386. PMID 16330770.
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Further reading
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