Coproporphyrinogen III

Coproporphyrinogen III
Names
	IUPAC name 3-[8,12,17-tris(2-carboxyethyl)-3,7,13,18-tetramethyl-5,10,15,20,21,22, 23,24-octahydroporphyrin-2-yl]propanoic acid
Identifiers
CAS Number	2624-63-7 ;
3D model (JSmol)	Interactive image;
ChemSpider	315 ;
MeSH	Coproporphyrinogen+III
PubChem CID	321;
CompTox Dashboard (EPA)	DTXSID40180875 ;
	InChI InChI=1S/C36H44N4O8/c1-17-21(5-9-33(41)42)29-14-27-19(3)22(6-10-34(43)44)30(39-27)15-28-20(4)24(8-12-36(47)48)32(40-28)16-31-23(7-11-35(45)46)18(2)26(38-31)13-25(17)37-29/h37-40H,5-16H2,1-4H3,(H,41,42)(H,43,44)(H,45,46)(H,47,48) Key: NIUVHXTXUXOFEB-UHFFFAOYSA-N ; InChI=1/C36H44N4O8/c1-17-21(5-9-33(41)42)29-14-27-19(3)22(6-10-34(43)44)30(39-27)15-28-20(4)24(8-12-36(47)48)32(40-28)16-31-23(7-11-35(45)46)18(2)26(38-31)13-25(17)37-29/h37-40H,5-16H2,1-4H3,(H,41,42)(H,43,44)(H,45,46)(H,47,48) Key: NIUVHXTXUXOFEB-UHFFFAOYAI;
	SMILES Cc1c2[nH]c(c1CCC(=O)O)Cc3c(c(c([nH]3)Cc4c(c(c([nH]4)Cc5c(c(c([nH]5)C2)C)CCC(=O)O)CCC(=O)O)C)CCC(=O)O)C;
Properties
Chemical formula	C36H44N4O8
Molar mass	660.757 g/mol
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Coproporphyrinogen III in an intermediate in the biosynthesis of natural porphyrins. It is produced from uroporphyrinogen III by the enzyme uroporphyrinogen III decarboxylase. In this process, four carboxymethyl groups (-CH₂CO₂H) are converted to methyl groups (CH₃).

Subsequently coproporphyrinogen III oxidase converts coproporphyrinogen III into protoporphyrinogen IX.^[1]

Heme synthesis—note that some reactions occur in the cytoplasm and some in the mitochondrion (yellow)

This biochemistry article is a stub. You can help Wikipedia by expanding it.

^ Paul R. Ortiz de Montellano (2008). "Hemes in Biology". Wiley Encyclopedia of Chemical Biology. John Wiley & Sons. doi:10.1002/9780470048672.wecb221.

[Hemes-1] Paul R. Ortiz de Montellano (2008). "Hemes in Biology". Wiley Encyclopedia of Chemical Biology. John Wiley & Sons. doi:10.1002/9780470048672.wecb221.

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