5-chlorocytosine

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Structural formula
Structural formula of 5-chlorocytosine
General
Surname 5-chlorocytosine
other names

4-amino-5-chloropyrimidin-2 (1 H ) -one

Molecular formula C 4 H 4 ClN 3 O
External identifiers / databases
CAS number 2347-43-5
PubChem 3083758
ChemSpider 2340915
Wikidata Q27295255
properties
Molar mass 145.55 g mol −1
Physical state

firmly

safety instructions
GHS hazard labeling
no classification available
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

5-chlorocytosine is a heterocyclic organic compound with a pyrimidine backbone. It is a derivative of the nucleobase cytosine with an additional chlorine at position 5.

literature

  • Fedeles BI; Freudenthal BD; Yau E .; Singh V .; Chang SC; Li D .; Delaney JC; Wilson SH; Essigmann JM: Intrinsic mutagenic properties of 5-chlorocytosine: A mechanistic connection between chronic inflammation and cancer. Proc Natl Acad Sci USA ; 2015; 112 (33): E4571-4580, doi: 10.1073 / pnas.1507709112 .

Individual evidence

  1. This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.