Andrei Darjewitsch Mirsabekow
Andrei Darjewitsch Mirsabekow , Russian Андрей Дарьевич Мирзабеков , English transcription Andrei Darievich Mirzabekov, (born October 19, 1937 in Baku ; † July 13, 2003 ) was a Russian molecular biologist, known for the development of biochip technology.
Mirsabekow graduated from the Institute for Fine Chemical Technology in Moscow in 1962, received his doctorate in 1965 and completed his habilitation in 1973 ( Russian doctorate ). From 1984 to 2004 he was director of the Engelhardt Institute for Molecular Biology in Moscow , where he has been working since 1961 and head of the laboratory from 1973.
In 1967 he was a visiting scientist at the Institute for Organic Chemistry and Biochemistry of the Academy of Sciences in Prague, in 1971 at the MRC Laboratory for Molecular Biology in Cambridge and in 1975/76 at Caltech and Harvard University .
From 1996 to 2000 he was director of the microarray program at the Argonne National Laboratory in Chicago, which, however, ended in a dispute between the partners involved over rights. Mirzabekow developed the MAGIChip technology (Microarrays of Gel-immobilized Compounds on a chip) at the Argonne Laboratory with David Stahl from the University of Washington .
Mirsabekov was active in the development of sequencing technology as well as DNA and RNA technology in the USSR.
In 1988 he developed the Gel Drop Microarray Technology, a technology with applications in DNA chip technology . Based on this, he dealt with the development of biochips and their application, for example SHOM (Sequencing by hybridization to oligonucleotide microchips). He introduced sequencing of DNA by hybridization with oligonucleotides as early as 1988. He has produced over 250 publications and over 30 patents.
He was a member of the Russian Academy of Sciences (corresponding member 1981, full member 1987), member of the Leopoldina (1998) and the Academia Europaea and honorary member of the Fundacion Valenciana de Estudios Avanzados . In 1969 he received the State Prize of the USSR for Science and Technology (for participation in the sequencing of t-RNA for the amino acid valine, under the direction of Alexander Alexandrowitsch Bajew ), in 1999 the Engelhardt gold medal of the Russian Academy of Sciences and in 1989 the Gregorian Mendel Medal . In 2004 he was posthumously accepted into the Legion of Honor .
From 1989 to 1994 he was Vice President of the Human Genome Organization . Since 1988 he has been the Vice President of the Russian Human Genome Project.
Web links
Individual evidence
- ↑ Quirin Schiermeier, Joint venture on biochips ends in disarray , Nature, Volume 412, 2001, p. 845
- ↑ member entry of Andrei D. Mirzabekov at the German Academy of Sciences Leopoldina , accessed October 23, 2015.
| personal data | |
|---|---|
| SURNAME | Mirsabekow, Andrei Darjewitsch |
| ALTERNATIVE NAMES | Мирзабеков, Андрей Дарьевич (Russian) |
| BRIEF DESCRIPTION | Russian molecular biologist |
| DATE OF BIRTH | October 19, 1937 |
| PLACE OF BIRTH | Baku |
| DATE OF DEATH | July 13, 2003 |