Angelika Schnieke

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Angelika Schnieke (born January 29, 1956 in Oberhausen ) is a German biotechnologist and lecturer at the Technical University of Munich .

Career

Schnieke studied bio-engineering in Hamburg and received his doctorate from the medical faculty of the University of Edinburgh . From 1978 to 1984 she worked as a bio-engineer at the Heinrich-Pette Institute for Experimental Virology and Immunology at the University of Hamburg . In the following years she worked and researched at the Whitehead Institute of MIT in Cambridge (USA), at the Ludwig Institute for Cancer Research in Bern (Switzerland) and at the Department of Physiology at Colorado State University in Fort Collins (USA). In 1992 she moved to PPL Therapeutics Ltd in Edinburgh (UK), where she initially worked as Head of Molecular Biology and later as Assistant Director of Research. During her time at PPL Therapeutics, she worked with scientists from the Roslin Institute at the University of Edinburgh on methods of somatic cell nucleus transfer in large animals. This work ultimately resulted in the birth of Dolly the sheep .

Schnieke has held the chair for biotechnology of farm animals at the Technical University of Munich since 2003 . From 2013 to 2016 she was Dean of Life Science at the Weihenstephan Science Center at the Technical University of Munich.

In 2011 she became a member of the National Academy of Sciences Leopoldina .

research

Schnieke is concerned with the application of biotechnological methods in the field of large animals, such as the genetic modification of mammals for regenerative medicine and the production of model animals for human diseases. Her greatest scientific achievements include the development of somatic cell nuclear transfer ( Dolly the sheep ), the production of the first transgenic animal through cell nuclear transfer, and the first genetically modified large animal.

Selected publications

  • KJ McCreath, J. Howcroft, KHS Campbell, A. Colman, AE Schnieke, AJ Kind: Production of gene-targeted sheep by nuclear transfer from cultured somatic cells . In: Nature . tape 405 , no. 6790 , June 2000, ISSN  0028-0836 , p. 1066-1069 , doi : 10.1038 / 35016604 ( nature.com [accessed December 31, 2019]).
  • Matthew J. Evans, Cagan Gurer, John D. Loike, Ian Wilmut, Angelika E. Schnieke, Eric A. Schon: Mitochondrial DNA genotypes in nuclear transfer-derived cloned sheep . In: Nature Genetics . tape 23 , no. 1 , September 1999, ISSN  1061-4036 , p. 90–93 , doi : 10.1038 / 12696 , PMID 10471506 , PMC 3042135 (free full text) - ( nature.com [accessed December 31, 2019]).
  • Paul G. Shiels, Alexander J. Kind, Keith HS Campbell, David Waddington, Ian Wilmut, A. Colman, AE Schnieke: Analysis of telomere lengths in cloned sheep . In: Nature . tape 399 , no. 6734 , May 1999, ISSN  0028-0836 , p. 316–317 , doi : 10.1038 / 20580 ( nature.com [accessed December 31, 2019]).
  • I. Wilmut, AE Schnieke, J. McWhir, AJ Kind, KHS Campbell: Viable offspring derived from fetal and adult mammalian cells . In: Nature . tape 385 , no. 6619 , February 1997, ISSN  1476-4687 , p. 810–813 , doi : 10.1038 / 385810a0 ( nature.com [accessed December 31, 2019]).
  • AE Schnieke, AJ Kind, WA Ritchie, K. Mycock, AR Scott, M. Ritchie, I. Wilmut, A. Colman, KHS Campbell: Human Factor IX Transgenic Sheep Produced by Transfer of Nuclei from Transfected Fetal Fibroblasts . In: Science . tape 278 , no. 5346 , December 19, 1997, p. 2130–2133 , doi : 10.1126 / science.278.5346.2130 ( sciencemag.org [accessed December 31, 2019]).

Individual evidence

  1. ^ Department of Livestock Biotechnology: Prof. Angelika Schnieke. Accessed December 31, 2019 .
  2. ^ Members. Accessed December 31, 2019 .
personal data
SURNAME Schnieke, Angelika
BRIEF DESCRIPTION German biotechnologist and university professor
DATE OF BIRTH January 29, 1956
PLACE OF BIRTH Oberhausen