Barbexaclon
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Non-proprietary name | Barbexaclon | |||||||||||||||||||||
other names |
(-) - N , α-Dimethylcyclohexaneethylammonium-5-ethyl-5-phenyl-barbiturate ( IUPAC ) |
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Molecular formula | C 12 H 12 N 2 O 3 • C 10 H 21 N | |||||||||||||||||||||
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Molar mass | 387.52 g mol −1 | |||||||||||||||||||||
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As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . |
Barbexaclon is a drug from the group of barbiturates used to treat various forms of epilepsy . Chemically speaking, it is a salt-like compound made up of phenobarbital and propylhexedrine . The individual components become effective after absorption . An additive or synergistic effect of the stimulant propylhexedrine to the antiepileptic effect of the phenobarbital could not be proven in animal experiments. Barbexaclon is now obsolete and only approved as a medicinal product in a few countries. In Italy, Switzerland and Austria it was marketed by the pharmaceutical company Abbott until 2009 under the trade name Maliasin .
Narcotics regulations
Internationally, Barbexaclon falls under the Convention on Psychotropic Substances . In Germany it is classified as a marketable narcotic drug and is subject to a separate prescription, provided the drug contains no less than 300 mg of substance (calculated as phenobarbital) per tablet or ampoule . Handling without permission or prescription is generally punishable.
Individual evidence
- ↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
- ^ A b M. Albinus: Hager's handbook of pharmaceutical practice: substances E – O. Birkhäuser, 1993. p. 372.
- ↑ P. Berlit: Therapielexikon Neurologie. Springer, 2004. p. 162.
- ↑ SPC for Maliasin ABBOTT in drug compendium of Switzerland - as of January of 2004.
- ↑ ABDA database (as of December 4, 2009).
- ↑ Appendix III of the Narcotics Act .