Bernhard Sabel

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Bernhard Sabel

Bernhard A. Sabel (* 1957 in Trier ) is a German psychologist . His more than 30 years of research is documented in over 200 publications and examines treatment options for visual impairments through the activation and rehabilitation of residual visual performance. Sabel heads the Institute for Medical Psychology at the Otto von Guericke University Magdeburg .

Life

Bernhard Sabel studied psychology at the University of Trier , psychobiology at the Clark University in Worchester, Massachusetts and physiological psychology at the University of Düsseldorf . In 1984 he received his doctorate and, after research stays in the USA at the Massachusetts Institute of Technology, began working as a research assistant at the Institute for Medical Psychology at the Ludwig Maximilians University in Munich . In 1988 he completed his habilitation with Ernst Pöppel . 1991 followed a stay as "Visiting Neuroscientist" at the Harvard Medical School in Boston.

In 1992 Sabel was appointed to the chair for medical psychology at the University of Magdeburg. Research stays and visiting professorships in the USA at Princeton University and in China at the Chinese Academy of Sciences and the Capital Medical University in Beijing followed. Sabel has been the editor of the international journal "Restorative Neurology and Neuroscience" since 1997. From 2008 to 2010 he was Vice Rector for Research at the Otto von Guericke University Magdeburg.

Sabel is married and has three children.

Research services

Sabel's research includes investigations of neuropsychological and neurobiological aspects of the plasticity and repair of the brain, with a special focus on functional recovery after partial damage to the visual system after optic nerve damage, glaucoma , brain injuries, diabetic retinopathy or stroke . The main focus is on the diagnosis and treatment of visual defects in stroke and glaucoma patients through training and non-invasive electrical stimulation. With the help of these methods, the disturbance in the natural synchronization of the electrical brain activity is determined by means of established EEG diagnostics in affected patients as changes in the brain wave activity (amplitude, frequency and functional connectivity). The second focus is the use of polymeric nanoparticles to overcome biological barriers in order to smuggle active substances into cells of the body and thus achieve therapeutic goals.

Research priorities

Neuropsychology

  • Mechanisms of visual plasticity
  • Computer simulation of plasticity in the visual cortex
  • Predictors of visual function recovery
  • Development and validation of computer-aided diagnosis and training methods for brain-damaged patients
  • Development and validation of methods of non-invasive brain stimulation using alternating current to improve visual performance after damage to the retina, optic nerve or brain

Behavioral neurobiology

  • In vivo test system for the analysis of the visual ability and the functional recovery of rats after lesion of the optic nerve and their neuroanatomical correlates
  • Treatment of these partially blind animals with various optical stimuli to restore their eyesight faster and better
  • Basic research on the effect of alternating current on neuroprotection and the recovery of visual performance
  • Investigations into the use of nanoparticles to administer drugs to overcome the blood-brain barrier.

Memberships and honors

Memberships

Awards

  • Competition "YOUTH RESEARCH", Special Prize Rhineland-Palatinate, 1976
  • Research Fellow, The Graduate School, Clark University, 1983-1984
  • DAAD scholarship holder, 1982–84
  • FULBRIGHT COMMISSION fellow, 1978–80
  • Clark University Exchange Scholar, 1978-80
  • Followship of the International Society for Eye Research, 1992
  • Quoted in "Who's Who in the World" 1990–2015
  • Quoted in "Who's Who in Science and Engineering" 1993–2001
  • Maria Saveria Cinquegrani Prize of the Association of Innovation Relay Centers (IRC) of the European Community for the best innovation in Communication and Information Technologies, Florence, 2000
  • Leonardo da Vinci award, The World Organization for the Achievement of Human Potential, Philadelphia, 2005
  • Science4life, 10th Business Plan Competition: Frankfurt. 3rd place in the nationwide competition. 2008 (for EBS Technologies GmbH)
  • Venture Lounge Berlin; 1st place winner, 2009
  • Award for the most innovative start-up company (lighthouse of the High-Tech-Gründerfonds) by Minister Brüderle (March 2011)
  • "Hai-ju" Award, Beijing Overseas Talents Program, 2012

Selected publications

  • BA Sabel, MD Slavin, DG Stein: GM1-ganglioside treatment facilitates behavioral recovery from bilateral brain damage . In: Science . tape 225 , 1984, pp. 340-342 , PMID 6740316 .
  • BA Sabel, DG Stein: Pharmacological treatment of central nervous system injury . In: Nature . tape 323 , 1986, pp. 340-342 , PMID 3762702 .
  • BA Sabel, R. Engelmann, MM Humphrey: In vivo confocal neuroimaging of CNS neurons (ICON) . In: Nature medicine . tape 3 , 1997, p. 244-2472 , PMID 9018248 .
  • E. Kasten, S. Wüst, W. Behrens-Baumann , BA Sabel: Computer-based training for the treatment of partial blindness . In: Nature medicine . tape 4 , no. 9 , 1998, pp. 1083-1087 , doi : 10.1038 / 2079 , PMID 734406 .
  • DA Poggel, E. Kasten, BA Sabel: Attentional cueing improves vision restoration therapy in patients with visual field loss . In: Neurology . tape 63 , no. 11 , 2004, p. 2069-2076 , PMID 15596752 .
  • BA Sabel, P. Henrich-Noack , A. Fedorov, C. Gall: Vision restoration after brain and retina damage: The "residual vision activation theory" . In: Progress in Brain Research . tape 192 , 2011, p. 199-262 , doi : 10.1016 / B978-0-444-53355-5.00013-0 .
  • C. Gall, S. Sgorzaly, S. Schmidt, S. Brandt, A. Fedorov, BA Sabel: Noninvasive transorbital alternating current stimulation improves subjective visual functioning and vision-related quality of life in optic neuropathy . In: Brain Stimulation . tape 4 , no. 4 , 2011, p. 175–188 , doi : 10.1016 / j.brs.2011.07.003 .
  • BA Sabel, AB Fedorov, N. Naue, A. Borrmann, C. Herrmann, C. Gall,: Non-invasive alternating current stimulation improves vision in optic neuropathy . In: Restorative Neurology and Neuroscience . tape 29 , no. 6 , 2011, p. 493-505 , doi : 10.3233 / RNN-2011-0624 .
  • M. Bola, C. Gall, C. Moewes, A. Fedorov, H. Hinrichs, BA Sabel: Brain functional connectivity network breakdown and restoration in blindness . In: Neurology . tape 83 , no. 6 , 2014, p. 542-551 , doi : 10.1212 / WNL.0000000000000672 .
  • M. Bola, BA Sabel: Dynamic reorganization of brain functional networks during cognition . In: NeuroImage . tape 114 , 2015, p. 398-413 , doi : 10.1016 / j.neuroimage.2015.03.057 .
  • C. Gall, S. Schmidt, MP Schittkowski, A. Antal, GG Ambrus, W. Paulus, M. Dannhauer, R. Michalik, A. Mante, M. Bola, A. Lux, S. Kropf, SA Brandt and BA Sabel: Alternating current stimulation for vision restoration after optic nerve damage: a randomized clinical trial . In: PLOS ONE . tape 11 , no. 6 , 2016, doi : 10.1371 / journal.pone.0156134 , PMID 27355577 , PMC 4927182 (free full text).

Web links

Individual evidence

  1. ^ Bernhard Sabel and 'Residual Vision Activation Theory': a History Spanning Three Decades. Retrieved February 19, 2016 .
  2. ↑ Press release 2011: Current stimuli can improve visual performance. Retrieved February 19, 2016 .
  3. ↑ Press release of July 1, 2016: AC stimulation can improve visual performance. (No longer available online.) Archived from the original on October 18, 2016 ; Retrieved October 18, 2016 . Info: The archive link was inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice. @1@ 2Template: Webachiv / IABot / www.med.uni-magdeburg.de
  4. ↑ Contribution to Sabel in Tagesspiegel 2010. Accessed on February 19, 2016 .
  5. ^ Article in Tagesspiegel 2014: Vision training on the computer can help. Retrieved February 19, 2016 .
  6. ↑ BMBF press release: With electric shocks against blindness Newsletter 70 / October 2014. (No longer available online.) Archived from the original on February 15, 2016 ; Retrieved February 19, 2016 . Info: The archive link was inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice. @1@ 2Template: Webachiv / IABot / www.gesundheitsforschung-bmbf.de
  7. ↑ SAVIR therapy to restore vision. In: Savir Center. Retrieved March 4, 2016 .
  8. ↑ Research news from the Saxony-Anhalt research portal on the award ceremony. Retrieved February 19, 2016 .
personal data
SURNAME Sabel, Bernhard
ALTERNATIVE NAMES Sabel, Bernhard A.
BRIEF DESCRIPTION German psychologist
DATE OF BIRTH 1957
PLACE OF BIRTH trier