Gordon Zubrod

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Gordon Zubrod

Charles Gordon Zubrod (born January 22, 1914 in Brooklyn , † January 19, 1999 in Washington, DC ) was an American oncologist , known for contributions to chemotherapy for cancer.

Life

Zubrod was the son of a wealthy stockbroker. He studied medicine at Columbia University with a degree in 1940 and was in the US Army Medical Corps in a unit to fight malaria during World War II ( chloroquine was introduced there as a replacement for quinine ). From 1946 he was at Johns Hopkins University Medical School, where he dealt with chemotherapy against pneumococci. In 1953 he was a brief professor at St. Louis University. In 1954 he went to the National Cancer Institute of the National Institutes of Health as clinical director . In 1956 he became head of cancer treatment at the National Cancer Institute and in 1961 its scientific director. In 1974 he became a professor at the University of Miami School of Medicine and head of oncology. He was also the director of the Florida Comprehensive Cancer Center there. In 1990 he retired.

He promoted the development of new cancer chemotherapy drugs and their clinical tests at a time when the pharmaceutical industry was not yet seeing the area as profitable. Zubrod was particularly successful in chemotherapy of acute leukemia in children and demonstrated its curability with chemotherapy. At the National Institute of Health, he was also instrumental in developing the principles and methods of clinical tests for cancer chemotherapy drugs. He also founded a Breast Cancer Task Force and was involved in the development of adjuvant therapy for breast cancer.

The Zubrod scale (Performance Status of the Eastern Cooperative Oncology Group (ECOG)) for the classification of cancer patients is named after him.

In 1972 he received the Lasker ~ DeBakey Clinical Medical Research Award . 1977/78 he was President of the American Association for Cancer Research .

He also studied marine biology.

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