CD90
| Thy-1 membrane glycoprotein | ||
|---|---|---|
| other names |
CDw90, Thy-1 antigen, CD90 |
|
| Properties of human protein | ||
| Mass / length primary structure | 161 amino acids , 17,935 Da | |
| Identifier | ||
| External IDs | ||
| Orthologue (human) | ||
| Entrez | 7070 | |
| Ensemble | ENSG00000154096 | |
| UniProt | P04216 | |
| Refseq (mRNA) | NM_001311160.1 | |
| Refseq (protein) | NP_001298089.1 | |
| PubMed search |
7070
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CD90 (synonym Thy-1 membrane glycoprotein ) is a surface protein from the immunoglobulin superfamily .
properties
CD90 is involved in cell adhesion , cell migration , apoptosis , the growth of axons , the formation of cell contacts and contacts with the extracellular matrix , the activation of T cells and the development of fibrosis . It is made in many types of cells, especially immune cells and nerve cells . In the brain, CD90 is involved in synaptogenesis . CD90 is glycosylated , phosphorylated and has a GPI anchor and a pyroglutamic acid . Different isoforms are formed by alternative splicing .
CD90 is a tumor suppressor .
Applications
CD90 is a cell type marker for hematopoietic stem cells .
Web links
Individual evidence
- ^ A b A. Kumar, A. Bhanja, J. Bhattacharyya, BG Jaganathan: Multiple roles of CD90 in cancer. In: Tumor biology: the journal of the International Society for Oncodevelopmental Biology and Medicine. Volume 37, Number 9, September 2016, pp. 11611-11622, doi : 10.1007 / s13277-016-5112-0 , PMID 27337957 .