CHOP
CHOP (or CHOEP = CHOP plus etoposide ) is the abbreviation for a chemotherapy scheme for the treatment of malignant lymphomas , including aggressive T- and B-NHL . It includes the medicinal substances
- C yclophosphamid
- H ydroxydaunorubicin (doxorubicin, adriamycin)
- Vincristine ( O ncovin ® )
- P redniso (lo) n
Studies have shown that the combination with the monoclonal antibody r ituximab (MabThera ® ) as the R-CHOP protocol or R-CHOEP protocol has a positive effect on the prognosis. Rituximab is a monoclonal antibody against CD20-positive cells. When CD20 is a receptor on B-lymphocytes , which on the one hand by binding of the antibody ion channel opening for cell lysis on the other hand to complement leads.
