COL20A1
Collagen type XX, alpha 1 | ||
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Ribbon model of collagen type XX, alpha 1 according to PDB 2DKM | ||
other names |
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Properties of human protein | ||
Mass / length primary structure | 1,284 amino acids , 135,830 Da | |
Isoforms | 3 | |
Identifier | ||
Gene names | COL20A1; BA261N11.4; KIAA1510 | |
External IDs | ||
Occurrence | ||
Parent taxon | Euteleostomi | |
Orthologue | ||
human | House mouse | |
Entrez | 57642 | 73368 |
Ensemble | ENSG00000101203 | ENSMUSG00000016356 |
UniProt | Q9P218 | Q923P0 |
Refseq (mRNA) | NM_020882.2 | NM_028518.1 |
Refseq (protein) | NP_065933.2 | NP_082794.1 |
Gene locus | Chr 20: 63.29 - 63.33 Mb | Chr 2: 180.98 - 181.02 Mb |
PubMed search | 57642 |
73368
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Collagen type XX, alpha 1 is a fibrillenassoziiertes collagen that the gene COL20A1 is encoded. It forms homotrimers , which in turn form collagen fibrils of type XX.
properties
Type XX, alpha 1 collagen is mostly found in the epithelial layer of the cornea, the embryonic skin, the sword process and in the tendon . The gene COL20A1 affects the process of tenderization of broiler meat . COL20A1 may appear to be an oncogene .
Web links
Individual evidence
- ^ M. Koch, JE Foley, R. Hahn, P. Zhou, RE Burgeson, DR Gerecke, MK Gordon: alpha 1 (Xx) collagen, a new member of the collagen subfamily, fibril-associated collagens with interrupted triple helices . In: J Biol Chem . 276, No. 25, June 22, 2011, pp. 23120-23126. doi : 10.1074 / jbc.M009912200 . PMID 11274142 .
- ↑ K. Piórkowska, K. Żukowski, J. Nowak, K. Połtowicz, K. Ropka-Molik, A. Gurgul: Genome-wide RNA-Seq analysis of breast muscles of two broiler chicken groups differing in shear force . In: Anim Genet . 47, No. 1, February 2016, pp. 68-80. doi : 10.1111 / age.12388 . PMID 26592359 .
- ↑ Chi-Cheng Huang, Shih-Hsin Tu, Heng-Hui Lien, Jaan-Yeh Jeng, Ching-Shui Huang, Chi-Jung Huang, Liang-Chuan Lai, Eric Y. Chuang: Concurrent gene signatures for han chinese breast cancers . In: PLoS One . 8, No. 10, October 3, 2013. doi : 10.1371 / journal.pone.0076421 . PMID 24098497 . PMC 3789693 (free full text).