COL20A1

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Collagen type XX, alpha 1
Collagen type XX, alpha 1
Ribbon model of collagen type XX, alpha 1 according to PDB  2DKM
other names
  • Alpha 1 Type XX Collagen
  • Collagen Alpha-1 (XX) chain
  • Type XX collagen alpha-1 chain

Existing structural data : PDB  2DKM , PDB  2EE3 , PDB  2EKJ

Properties of human protein
Mass / length primary structure 1,284 amino acids , 135,830 Da
Isoforms 3
Identifier
Gene names COL20A1; BA261N11.4; KIAA1510
External IDs
Occurrence
Parent taxon Euteleostomi
Orthologue
human House mouse
Entrez 57642 73368
Ensemble ENSG00000101203 ENSMUSG00000016356
UniProt Q9P218 Q923P0
Refseq (mRNA) NM_020882.2 NM_028518.1
Refseq (protein) NP_065933.2 NP_082794.1
Gene locus Chr 20: 63.29 - 63.33 Mb Chr 2: 180.98 - 181.02 Mb
PubMed search 57642 73368

Collagen type XX, alpha 1 is a fibrillenassoziiertes collagen that the gene COL20A1 is encoded. It forms homotrimers , which in turn form collagen fibrils of type XX.

properties

Type XX, alpha 1 collagen is mostly found in the epithelial layer of the cornea, the embryonic skin, the sword process and in the tendon . The gene COL20A1 affects the process of tenderization of broiler meat . COL20A1 may appear to be an oncogene .

Web links

Individual evidence

  1. ^ M. Koch, JE Foley, R. Hahn, P. Zhou, RE Burgeson, DR Gerecke, MK Gordon: alpha 1 (Xx) collagen, a new member of the collagen subfamily, fibril-associated collagens with interrupted triple helices . In: J Biol Chem . 276, No. 25, June 22, 2011, pp. 23120-23126. doi : 10.1074 / jbc.M009912200 . PMID 11274142 .
  2. K. Piórkowska, K. Żukowski, J. Nowak, K. Połtowicz, K. Ropka-Molik, A. Gurgul: Genome-wide RNA-Seq analysis of breast muscles of two broiler chicken groups differing in shear force . In: Anim Genet . 47, No. 1, February 2016, pp. 68-80. doi : 10.1111 / age.12388 . PMID 26592359 .
  3. Chi-Cheng Huang, Shih-Hsin Tu, Heng-Hui Lien, Jaan-Yeh Jeng, Ching-Shui Huang, Chi-Jung Huang, Liang-Chuan Lai, Eric Y. Chuang: Concurrent gene signatures for han chinese breast cancers . In: PLoS One . 8, No. 10, October 3, 2013. doi : 10.1371 / journal.pone.0076421 . PMID 24098497 . PMC 3789693 (free full text).