Carmen Birchmeier-Kohler

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Carmen Birchmeier-Kohler (born July 6, 1955 in Waldshut ) is a German genetic researcher and developmental biologist. The focus of her working group is the development of embryonic tissues and the nervous system. The model organism for their studies is the mouse.

Live and act

Birchmeier-Kohler studied biochemistry from 1974 to 1979 at the University of Konstanz , the University of California, San Diego and the ETH Zurich . She completed her doctoral thesis with Max Birnstiel in 1984 at the Institute for Molecular Biology II at the University of Zurich . After a stay abroad as a postdoctoral fellow with Michael Wigler and as a scientist at the Cold Spring Harbor Laboratory on Long Island (USA) from 1984 to 1989, she took over the leadership of a working group in the Max Delbrück Laboratory in Cologne on the premises of the Max Planck Institute for Breeding research . There she completed her habilitation in 1993 .

Since 1995 she has been working at the Max Delbrück Center for Molecular Medicine (MDC) in Berlin. In 2002 she received a C4 professorship at the Medical Faculty of the Free University (FU) Berlin , now Charité .

Carmen Birchmeier is married to the developmental biologist and cancer researcher Walter Birchmeier .

Research priorities

Birchmeier-Kohler is concerned with the molecular biology of embryogenesis and organogenesis in mammals and their significance for defective development of the nervous system , diseases of the skeletal muscles and the heart as well as cancer . With the help of knockout mice , Birchmeier-Kohler and colleagues were able to explain the role of various growth factors or their receptors and the transcription factors they control in the development of the organism.

Awards and honors

In 2002 she was awarded the Gottfried Wilhelm Leibniz Prize for her research on signal transmission between cells during embryonic and organ development in mammals .

Memberships (selection)

She has been a member of the Academia Europaea since 2013 . In 2018 she was elected a member of the German Academy of Sciences Leopoldina .

Publications (selection)

  • C. Cheret, M. Willem, FR Fricker, H. Wende, A. Wulf-Goldenberg, S. Tahirovic, KA Nave, P. Saftig, C. Haass, AN Garratt, DL Bennett, C. Birchmeier: Bace1 and Neuregulin- 1 cooperate to control formation and maintenance of muscle spindles. In: The EMBO Journal . Volume 32, Number 14, July 2013, pp. 2015–2028, doi : 10.1038 / emboj.2013.146 , PMID 23792428 , PMC 3715864 (free full text).

Web links

Individual evidence

  1. ↑ Directory of members: Carmen Birchmeier. Academia Europaea, accessed June 19, 2017 .
  2. Member entry by Prof. Dr. Carmen Birchmeier at the German Academy of Sciences Leopoldina , accessed on July 19, 2018.