Max Birnstiel

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Max L. Birnstiel (born July 12, 1933 in Bahia , Brazil ; † November 15, 2014 in Männedorf near Zurich ) was a Swiss molecular biologist and founding director of the Vienna Institute of Molecular Pathology (IMP).

Life

Max L. Birnstiel attended the canton school in Zurich from 1945 to 1951 . From 1952 to 1959 he studied physical chemistry and botany at the ETH Zurich , where he received his doctorate with his dissertation on the redox potential of living and dying plant tissue (tobacco browning) .

From 1960 to 1963 he worked as a post-doctoral student at the Department of Biology at the California Institute of Technology in Pasadena (California) ( USA ) with James Bonner . From 1963 he was a lecturer ( lecturer ) at the University of Edinburgh , in 1972, he moved to the Institute of Molecular Biology of the University of Zurich , where he was until 1986 a professor and head of the institute.

From 1986 to 1996 he was director of the newly founded Vienna Institute of Molecular Pathology (IMP).

In 1997 he and his colleagues founded Intercell AG as a spin-off of the IMP, where he worked until 2002. In 2017 the Max Birnstiel Foundation was founded, which is dedicated to promoting young scientists in molecular biology. Together with the IMP, the foundation established the “Birnstiel Award” for doctoral students in the molecular life sciences in 2019.

Awards

Publications

  • with MI Chipchase and BB Hyde: The nucleolus, a source of ribosomes. In: Biochim Biophys Acta. 76, 1963, pp. 454-462.
  • with W. Schaffner, K. Gross and J. Telford: Molecular analysis of the histone gene cluster of Psammechinus miliaris: II. The arrangement of the five histone-coding and spacer sequences. In: Cell. 8, 1976, pp. 471-478.
  • with E. Jacob and G. Malacinski: Reiteration frequency of the histone genes in the genome of the amphibian Xenopus laevis. In: Eur J Biochem. 69, 1976, pp. 45-54.
  • with W. Schaffner, G. Kunz, H. Daetwyler, J. Telford and HO Smith: Genes and spacers of cloned sea urchin histone DNA analyzed by sequencing. In: Cell. 14, 1978, pp. 655-671.
  • with R. Grosschedl, B. Wasylyk and P. Chambon : Point mutation in the TATA box curtails expression of sea urchin H2A histone gene in vivo. In: Nature. 294 (5837): 1981, pp. 178-180.
  • with R. Grosschedl: Delimitation of far upstream sequences required for maximal in vitro transcription of an H2A histone gene. In: Proc Natl Acad Sci USA. 79, 1982, pp. 297-301.
  • Sea urchin histone genes: the beginning and end of the message. In: Philos Trans R Soc Lond B Biol Sci. 307 (1132), 1984, pp. 293-295.
  • Gene isolation is 25 years old this month. In: Trends Genet. 6, 1990, pp. 380-381.
  • with K. Zatloukal, W. Schmidt, M. Cotten, E. Wagner with G. Stingl: Somatic gene therapy for cancer: the utility of transferrinfection in generating 'tumor vaccines'. In: Genes. 135, 1993, pp. 199-207.
  • with W. Schmidt, M. Buschle, W. Zauner, H. Kirlappos, K. Mechtler and B. Trska: Cell-free tumor antigen peptide-based cancer vaccines. In: Proc Natl Acad Sci USA. 94, 1997, pp. 3262-3267.
  • Moving from Zurich to Vienna - up or down? In: Biol Chem. 380, 1999, pp. 111-112.
  • The dawn of gene isolation. In: Genes. 300, 2002, pp. 3-11.

Web links

Individual evidence

  1. ^ Kurier - IMP founder Max Birnstiel has died . Article dated November 21, 2014, accessed November 21, 2014.
  2. ↑ derStandard.at - IMP founding director Max Birnstiel has died . Article dated November 21, 2014, accessed November 21, 2014.
  3. ↑ IMP founding director Max L. Birnstiel has passed away . APA notification dated November 21, 2014, accessed November 21, 2014.
  4. ↑ science.orf.at - IMP founding director Max Birnstiel has died . Article dated November 21, 2014, accessed November 22, 2014.
  5. ↑ Max Birnstiel: About the redox potential of living and dying plant tissue (tobacco browning) . Diss., Confederation. Technical University, Zurich 1960.
  6. ^ The Research Institute of Molecular Pathology (IMP) - History . Retrieved November 22, 2014.
  7. ^ Entry about Max L. Birnstiel in the database of the Wilhelm Exner Medal Foundation .
  8. ↑ Max Birnstiel Foundation. Retrieved May 6, 2019 .
  9. ↑ Birnstiel Award (English). Research Institute for Molecular Pathology, accessed May 6, 2019 .
  10. ↑ Member entry of Max L. Birnstiel at the German Academy of Natural Scientists Leopoldina , accessed on November 28, 2014.
  11. ↑ Mitterlehner: Max Birnstiel played a key role in shaping the research location . APA notification dated November 21, 2014, accessed July 2, 2015.
  12. ↑ List of winners of the Medal of Honor for Services to the Republic of Austria . Retrieved November 21, 2014.
personal data
SURNAME Birnstiel, Max
ALTERNATIVE NAMES Birnstiel, Max L.
BRIEF DESCRIPTION Swiss molecular biologist
DATE OF BIRTH July 12, 1933
PLACE OF BIRTH Bahia , Brazil
DATE OF DEATH 15th November 2014
Place of death Männedorf near Zurich