Pierre Chambon

Pierre Chambon (born February 7, 1931 in Mulhouse , Alsace ) is a French geneticist .

Chambon studied medicine at the University of Strasbourg , where he received his doctorate in 1958. He was the long-time director (and founder) of the Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC) at the University of Strasbourg in Illkirch-Graffenstaden and, together with Jean-Pierre Ebel, is the founder of the École supérieure de biotechnologie de Strasbourg (ESBS) . He is a member of the Académie des sciences and now teaches at the Collège de France in Paris . He is the director of the Institut clinique de la souris (ICS).

His studies of proteins , which are involved in the translation of genetic information by cellular messenger substances, are considered to be important for cell and tumor biology. From the 1970s onwards, he was one of the pioneers in the application of modern genetic engineering methods to research gene regulation in eukaryotic cells. He identified RNA polymerase II (B), various transcription control elements and cloned and investigated the function of nuclear receptors for hormones. With Ronald M. Evans he discovered the receptor for retinoic acids in cells with applications in tumor research and developmental biology .

Awards, honors, memberships

• 1976: Prix Rosen (Fondation pour la Recherche Medicale)
• 1979: Médaille d'or du CNRS
• 1981: Louis and Bert Freeman Foundation Prize for Research (New York Academy of Science)
• 1982: Richard Lounsbery Prize (National Academy of Sciences and Academie des Sciences)
• 1985: Honorary doctorate from the University of Liège
• 1986: Charles Oberling Prize
• 1987: Prix Henry et Mary Jane Mitjavile (Academie Nationale de Medicine)
• 1987: Harvey Prize of Science and Technology (TECHNION)
• 1987: Prix ​​Léopold Griffuel (Association pour la Recherche sur le Cancer)
• 1988: König-Faisal-Preis (International Prize in Science)
• 1990: Hans Krebs Medal (Federation of European Biochemical Societies)
• 1990: Prix Roussel
• 1991: Prix Louis-Jeantet of the Louis-Jeantet Foundation
• 1993: Officer of the Palmes Academique
• 1996: Grand Prix of the French Foundation for Medical Research
• 1998 Welch Award in Chemistry
• 1999: Louisa Gross Horwitz Prize (Columbia University)
• 1999: Honorary Doctorate from Sapporo Medical University
• 1999: Prize of the Association Francaise pour la Recherche Therapeutique (AFRT)
• 2000: Commander of the Legion of Honor
• 2000: Invitation to the Horowitz Prize Lecture (Columbia University)
• 2003: Alfred P. Sloan, Jr. Prize
• 2003: Prize of the March of Dimes Prize in Developmental Biology
• 2004: Albert Lasker Award for Basic Medical Research
• 2004: Honorary Award from INSERM
• 2004: Endocrine Regulation Prize
• 2010: Canada Gairdner International Award
• 2011: Grand officier (Grand Commander) des Ordre national du Mérite
• 2011: Fred Conrad Koch Award
• 2018: Louisa Gross Horwitz Prize (second award after 1999)

Pierre Chambon is a member ( Fellow ) of the following scientific associations and organizations: New York Academy of Sciences (Fellow from 1996), American Association for the Advancement of Science (Fellow from 1995), Chinese Society of Genetics, Academia Europaea , Royal Swedish Academy of Sciences , Academie Royale de Medicine of Belgium, American Academy of Arts and Sciences (USA), Académie des sciences (Paris), Academie Royale des Sciences of Liege, European Molecular Biology Organization, National Academy of Sciences (USA), Eurolife Network, International Center for Genetic Engineering and Biotechnology, Strasbourg School of Biotechnology.

He has edited Genes and Development , Cell , Current Opinion in Endocrinology , The Breast , International Journal of Cancer , Biochimie , Molecular Medicine , Biological Chemistry , Developmental Biology , Journal of Clinical Investigation , FASEB Journal , Molecular Cell , Genome Biology , IUBMB Life .

In 1991 he became a senior member of the Institut Universitaire de France .

Web links

• Page at the College de France