Corwin Hansch
Corwin Hansch (born October 6, 1918 in Kenmare (North Dakota) , † May 8, 2011 in Claremont (California) ) was an American chemist ( organic chemistry ). He was a professor at Pomona College and is considered to be one of the founders of the quantitative structure-activity relationship (QSAR).
life and work
Hansch studied at the University of Illinois , Chicago, with a bachelor's degree in 1940 and received his doctorate in 1944 from New York University . He then worked in the Manhattan Project at the University of Chicago and at DuPont , where he was also a brief research chemist. In 1946 he went to Pomona College, where he became a professor.
He was a visiting researcher at the ETH Zurich and the Ludwig Maximilians University in Munich . He was an honorary professor at Peking University.
With his work in the early 1960s, he is considered the founder of QSAR, the correlation of biological activity with chemical structure (often simply called Hansch equations or Hansch analysis), with many applications in the computer-aided design of drugs. He has produced over 300 publications.
He was a Guggenheim Fellow , received the Tolman Award in 1975 and the ACS Award for Computers in Chemical and Pharmaceutical Research in 1999, and was a member of the Royal Society of Chemistry . He was inducted into the American Chemical Society's Hall of Fame for Chemical Physics.
Fonts
- C. Hansch, PP Maloney, T. Fujita, RM Muir: Correlation of Biological Activity of Phenoxyacetic Acids with Hammett Substituent Constants and Partition Coefficients . In: Nature . tape 194 , no. 4824 , April 1962, p. 178-180 , doi : 10.1038 / 194178b0 .
- Corwin Hansch, Robert M. Muir, Toshio Fujita, Peyton P. Maloney, Fred Geiger, Margaret Streich: The Correlation of Biological Activity of Plant Growth Regulators and Chloromycetin Derivatives with Hammett Constants and Partition Coefficients . In: Journal of the American Chemical Society . tape 85 , no. September 18 , 1963, p. 2817-2824 , doi : 10.1021 / ja00901a033 .
literature
- Cynthia Rachel Selassie: Obituary: Corwin H. Hansch . In: Journal of Computer-Aided Molecular Design . tape 25 , no. 6 , 2011, p. 493-494 , doi : 10.1007 / s10822-011-9445-x .
- Susan Ainsworth: Corwin Hansch Dies at 92 . In: Chemical & Engineering News Archive . tape 89 , no. 23 , 2011, p. 50-51 , doi : 10.1021 / cen-v089n023.p050 .
Web links
- Mark Kendall: In Memoriam: Corwin H. Hansch. In: Pomona College Magazine. October 11, 2011, accessed June 23, 2017 .
- Cynthia Selassie: Emeritus Professor of Chemistry Corwin Hansch Died on May 8. In: Pomona College News. May 11, 2011, archived from the original on August 5, 2014 ; accessed on June 23, 2017 (English).
- Obituary in the LA Times 2011
Individual evidence
| personal data | |
|---|---|
| SURNAME | Hansch, Corwin |
| BRIEF DESCRIPTION | American chemist |
| DATE OF BIRTH | October 6, 1918 |
| PLACE OF BIRTH | Kenmare, North Dakota |
| DATE OF DEATH | May 8, 2011 |
| Place of death | Claremont (California) |