Dana Carroll

Dana Carroll (* 1943 in California ) is an American molecular biologist and biochemist at the University of Utah .

Carroll is involved in DNA repair and recombination . He developed methods for genome editing by means of programmable cutting of the DNA using zinc finger nucleases . More recent studies also use Transcription Activator-like Effector Nucleases (TALEN) or the CRISPR / Cas method to specifically induce double-strand breaks . Carroll and co-workers were able to show that inhibiting leading but mutagenic repair mechanisms can improve the accuracy of genetic manipulations. More recent work deals with the role of chromatin structure in the efficiency of DNA cutting. In 2018 Carroll closed his research laboratory, but continues to work scientifically - in particular on ethical issues of genetic engineering .

Carroll grew up in Bethesda , Maryland . He received a bachelor's degree from Swarthmore College (1965) and a Ph.D. from the University of California, Berkeley . (under Ignacio Tinoco ), both in chemistry . As a postdoctoral fellow , he worked with John Paul at the Beatson Institute for Cancer Research and with Donald D. Brown at the Carnegie Institution of Washington . Carroll has been a faculty member at the University of Utah since 1975 , where he was director of biochemistry from 1985 to 2009. Stays abroad took him to the Institut Curie in Paris and Edinburgh University .

In 2012 Carroll received the Novitski Prize from the Genetics Society of America . In 2013 he was elected as a Fellow of the American Association for the Advancement of Science , and in 2017 as a member of both the National Academy of Sciences and the American Academy of Arts and Sciences .

Web links

• Dana Carroll, PhD and Carroll Lab at the University of Utah (utah.edu)

Individual evidence

1. ↑ Dana Carroll '65. In: bulletin.swarthmore.edu. Swarthmore College Bulletin, July 2013, accessed October 3, 2018 . 
2. ^ S. Jinks-Robertson: The 2012 Novitski Prize: Dana Carroll. In: Genetics. 191, 2012, pp. 305-306, doi : 10.1534 / genetics.112.138925 .
3. ↑ GSA honors researchers, educators for distinguished service in the field of genetics. In: news-medical.net. January 19, 2012, accessed October 3, 2018 . 
4. ^ Kat Zambon: AAAS Council Elects 388 New AAAS Fellows. In: aaas.org. American Association for the Advancement of Science , November 25, 2013, accessed October 3, 2018 . 
5. ↑ Book of Members 1780 – present, Chapter C. (PDF; 1.3 MB) In: American Academy of Arts and Sciences (amacad.org). Retrieved October 3, 2018 .