Donald D. Brown

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Donald David Brown (born December 30, 1931 in Cincinnati , Ohio ) is an American embryologist and developmental biologist at the Carnegie Institution of Washington and the Johns Hopkins University in Baltimore , Maryland .

Life

Brown earned a Masters in Biochemistry (with a thesis on viral invasion) and an MD in Medicine from the University of Chicago School of Medicine in 1956 . In the same year he also passed his State Medical Board Examination in the state of Ohio . As an assistant doctor, he first worked at the Charity Hospital in New Orleans before joining the National Institutes of Health as a research assistant in 1957 , where he worked on amino acids . In 1959 he went as a Fellow (Fellow) of the National Cancer Institute at the Institut Pasteur in France, where he met with the enzyme dealt -regulation of bacteria. In 1960 he became a researcher in the Department of Embryology at the Carnegie Institution of Washington in Baltimore , Maryland . From 1976 to 1994 he was the director of this department. Since 1968 he was also professor of biology at Johns Hopkins University , also in Baltimore.

Act

Before genetic engineering became widespread, Brown's research area was the development of gene expression during embryonic development . He described his work as “ genetics through gene isolation”.

Since 1990 Brown's most important research area has been the thyroid hormone- dependent developmental steps on the way from the tadpole to the frog ( Xenopus laevis ). These serve as a model process for metamorphosis and apoptosis , but also for organogenesis in vertebrates .

One of the many scientists who were supervised in Brown's laboratory was the future Nobel Prize winner Andrew Z. Fire . Brown has served on the scientific boards of numerous journals, including the Journal of Cell Biology , Journal of Biological Chemistry , Cell, and Current Opinions in Cell Biology .

Awards (selection)

Web links

Individual evidence

  1. ↑ The Tanner Lectures on Human Values (PDF, 270 kB) at tannerlectures.utah.edu; accessed on February 2, 2016.
  2. ↑ Book of Members 1780 – present, Chapter B. (PDF; 1.2 MB) In: American Academy of Arts and Sciences (amacad.org). Accessed April 7, 2018 .
  3. ^ NAS Award in Molecular Biology at nasonline.org; accessed on January 14, 2016
  4. ^ Fellows of the AAAS: Donald Brown. American Association for the Advancement of Science, accessed February 21, 2018 .
  5. ↑ Dr. Donald D. Brown at the American Philosophical Society (amphilsoc.org); Retrieved April 29, 2011
  6. ^ Past Recipients of the Louisa Gross Horwitz Prize at columbia.edu; Retrieved April 28, 2011
  7. ^ Past Winners - Rosenstiel Award - Rosenstiel Basic Medical Sciences Research Center - Brandeis University. In: brandeis.edu. Retrieved January 23, 2016 .
  8. ↑ EB Wilson Medal at ascb.org; Retrieved April 28, 2011
  9. ^ Donald Brown Receives Lifetime Achievement Award from Society for Developmental Biology at carnegiescience.edu; Retrieved April 28, 2011
  10. ↑ Lasker Foundation: Fundamental biomolecular techniques. In: laskerfoundation.org. Accessed April 7, 2018 .
personal data
SURNAME Brown, Donald D.
ALTERNATIVE NAMES Brown, Donald David (full name)
BRIEF DESCRIPTION American embryologist and developmental biologist
DATE OF BIRTH December 30, 1931
PLACE OF BIRTH Cincinnati , Ohio