David JP Barker

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David James Purslove Barker CBE (born June 29, 1938 - † August 27, 2013 ) was a British epidemiologist . He is known for hypotheses of the connection between malnutrition in the embryonic stage and in early childhood and, for example, coronary heart disease in adulthood.

Life

Barker graduated from the University of London with a Bachelor of Science degree (BSc) in 1959 and a Bachelor of Medicine, Bachelor of Surgery (MBBS) in 1962. In 1966 he received his PhD from the University of Birmingham ( Ph.D. ) and in 1968 he became a member of the Royal College of Physicians (MRCP). In 1974 he earned an MD from the University of London. He was a professor of clinical epidemiology at the University of Southampton . He was also Professor of Cardiovascular Medicine at Oregon Health and Science University .

In 1989 he discovered a link between low birth weight (and underweight in early childhood) and later susceptibility to coronary heart disease. He later extended this to include increased risks of high blood pressure, type 2 diabetes mellitus and strokes. In 2010 he investigated prenatal influences for lung cancer.

He was a Fellow of the Royal Society (1998). In 2005 he became a CBE . In 1994 he received the Wellcome Prize , the Longevity Prize in 2007 and the Richard Doll Prize in Epidemiology in 2011 .

Barker was married twice. With his first wife Angela († 1980) he had five children. His second wife Jan (married 1983) brought three more children into the marriage.

Fonts

Books:

  • Practical Epidemiology . Churchill Livingstone, 4th edition 1990 (first 1973)
  • with Geoffrey Rose: Epidemiology in Medical Practice . Churchill Livingstone 1976, 5th edition 1997
  • with G. Rose: Epidemiology for the Uninitiated . BMJ Books, 1979, 3rd edition 1993
  • with MJ Gardner, PD Winter: Atlas of Mortality from Selected Diseases in England and Wales 1968-1978 . Wiley, 1984
  • The fetal and Infant Origins of Adult Disease . BMJ Books, 1992
  • Mothers, Babies and Health in Later Life . Churchill Livingstone 1994, 2nd edition 1998
  • as editor: Fetal Programming: Influences on Development and Disease in Later Life . NIH Monograph Series, Marcel Dekker, 2000
  • as editor: Fetal Origins of Cardiovascular and Lung Diseases . RCOG Press, 1998
  • as editor: Type 2 Diabetes: The Thrifty Phenotype . Oxford University Press, 2001
  • Editor with Graham J. Burton, A. Moffett, K. Thornburg: The Placenta and Human Developmental Programming . Cambridge University Press, 2011

Some essays:

  • with C. Osmond: Infant mortality, childhood nutrition and ischaemic heart disease in England and Wales . In: The Lancet , Volume 327, 1986, p. 1077, Abstract
  • with C. Osmond, PD Winter, BM Margetts, SJ Simmonds Weight in infancy and death from ischaemic heart disease . In: The Lancet , September 1989, pp. 577-580
  • Fetal origins of coronary heart Diseuse . In: British Medical Journal , Volume 311, 1995, pp. 171-174
  • with C. Osmond, TJ Forsén, E. Kajantie, JG Eriksson Maternal and social origins of hypertension . In: Hypertension , Volume 50, 2007, pp. 565-571

literature

  • Cyrus Cooper: David Barker (1938-2013). Epidemiologist who traces roots of chronic disease to early life. In: Nature . Volume 502, No. 7471, 2013, p. 304, doi: 10.1038 / 502304a

Web links

References and comments

  1. Known in Great Britain as the Barker Hypothesis .
  2. The study published in The Lancet looked at 5,654 men born between 1911 and 1930 in Hertfordshire. PMID 2570282