Dennis A. Dougherty

from Wikipedia, the free encyclopedia

Dennis A. Dougherty (born December 4, 1952 in Harrisburg (Pennsylvania) ) is an American chemist (chemical biology, organic chemistry).

Dougherty graduated from Bucknell University with a bachelor's degree and master's degree in 1974 and in 1978 at Princeton University at Kurt Mislow with the topic Structural studies in polyarylethane chemistry doctorate . As a post-graduate student , he was with Jerome Berson at Yale University . In 1979 he became Assistant Professor, 1985 Associate Professor and 1989 Professor at Caltech , from 2002 as George Grant Hoag Professor of Chemistry.

Dougherty is concerned with physical organic chemistry, strained hydrocarbons, photochemistry, molecular recognition, bi-radicals, bioorganic chemistry, and theoretical and computational organic chemistry. He and his group have recently been working on the chemical understanding of ion channels and neuroreceptors in the nervous system.

As a mechanism in ion channels, he investigated cation-pi systems (as they are present in the interaction of a potassium ion perpendicular to a benzene ring), for which he developed an electrostatic model.

For 2020, Dougherty was awarded the Arthur C. Cope Award . In 2010 he received the Tolman Award , the Arthur C. Cope Scholar Award in 1992 and the James Flack Norris Award in 2008 . He is a member of the National Academy of Sciences (2009), the American Academy of Arts and Sciences (1999) and the American Association for the Advancement of Science (1993). 1983 to 1985 he was a Sloan Research Fellow .

Fonts

  • with Eric V. Anslyn Modern Physical Organic Chemistry , Palgrave Macmillan 2005

Web links

Individual evidence

  1. Life data according to American Men and Women of Science , Thomson Gale 2004
  2. biographical data, publications and Academic pedigree of Dennis A. Dougherty at academictree.org, accessed on 30 January 2018th
  3. ^ R. Kumpf, D. Dougherty A mechanism for ion selectivity in potassium channels: Computational studies of cation-pi interactions . Science 261, 1993, pp. 1708-10