Douglas Hanahan

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Douglas "Doug" Hanahan (* 1951 in Seattle ) is an American biochemist and cancer researcher . He is professor at the École polytechnique fédérale de Lausanne and head of the Swiss Institute for Experimental Cancer Research (ISREC).

Hanahan earned a bachelor's degree in physics from the Massachusetts Institute of Technology in 1976 . He then enrolled at Harvard University in Biochemistry and Molecular Biology , but spent most of his time at the Cold Spring Harbor Laboratory (CSHL), one of the few institutions that was allowed to work with recombinant DNA in bacteria at the time . Here he earned a PhD in 1983 , improved the methods of introducing recombinant DNA into bacteria considerably and developed the SOB medium , a nutrient medium for bacteria. Hanahan stayed at CSHL even after graduating as a researcher. In 1988 he received a professorship at the University of California, San Francisco , which he held until 2010. At the Swiss Institute for Experimental Cancer Research (ISREC), he works with genetically modified human tumor cells and studies their development into invasive and metastatic cancers using a mouse model . His work focuses on the one hand on the importance of the stroma and the tumor microenvironment and on the other hand on the development of preclinical tests to develop new cancer therapies .

Together with Robert Allan Weinberg , Hanahan wrote two much-cited papers that summarized the most important biological properties of cancer : The Hallmarks of Cancer and Hallmarks of Cancer: The Next Generation .

Hanahan was elected a member of the American Academy of Arts and Sciences in 2007, the National Academy of Sciences in 2009 and the European Molecular Biology Organization in 2010 . In 2010 he received an honorary doctorate from the University of Dundee and in 2014 the AACR Award for Lifetime Achievement in Cancer Research from the American Association for Cancer Research .

Web links

Individual evidence

  1. ^ Douglas Hanahan, Robert A. Weinberg: The hallmarks of cancer. In: Cell. Volume 100, Number 1, January 2000, pp. 57-70, PMID 10647931 (review).
  2. ^ Douglas Hanahan, Robert A. Weinberg: Hallmarks of Cancer: The Next Generation. In: Cell. Volume 144, Number 5, March 2011, pp. 646-674, doi: 10.1016 / j.cell.2011.02.013 .
  3. ↑ Book of Members 1780 – present, Chapter H. (PDF; 1.2 MB) In: American Academy of Arts and Sciences (amacad.org). Accessed December 14, 2017 .
  4. ^ Douglas Hanahan. In: nasonline.org. Retrieved December 14, 2017 .
  5. ^ Douglas Hanahan. In: people.embo.org. Accessed December 14, 2017 .
  6. ^ AACR Award for Lifetime Achievement in Cancer Research. In: aacr.org. Accessed December 14, 2017 .
personal data
SURNAME Hanahan, Douglas
ALTERNATIVE NAMES Hanahan, Doug
BRIEF DESCRIPTION American biochemist and cancer researcher
DATE OF BIRTH 1951
PLACE OF BIRTH Seattle