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Du Bois or du Bois is the family name of the following people:
- Alcide Hyacinthe du Bois de Beauchesne (1804–1873), French writer
- Andreas du Bois (* 1956), German gynecologist and oncologist
- Charles Du Bois (1874–1963), Swiss dermatologist
- Charles du Bois (also Dubois; 1656–1740), English merchant and botanist
- Charles Frédéric Dubois (also Du Bois; 1804–1867), Belgian naturalist
- Emil du Bois-Reymond (1818-1896), German physiologist
- Eveline Du Bois-Reymond Marcus (1901–1990), German-Brazilian zoologist and illustrator
- Félicien Du Bois (* 1983), Swiss ice hockey player
- François Du Bois , French composer
- Franz Du Bois , lieutenant colonel of the fortress Mainz
- Gaspard du Bois (1587–1667), theologian, bishop and university professor
- Georg Du Bois (1874–1947), Swiss manager of the German metallurgical and chemical industry
- John Jay du Bois , American entomologist and collector (Acmaeodera duboisi Cazier, 1938, Duboisius Abdullah, 1961)
- Karl Wilhelm Heinrich Freiherr du Bois du Thil (1777-1859), Prime Minister of the Grand Duchy of Hesse, see Karl du Thil
- Kerwin Du Bois (* 1977), Trinidadian singer, songwriter and producer of soca and calypso music
- Léon Du Bois (1859–1935), Belgian composer and organist
- Paul Du Bois (1859–1938), Belgian sculptor
- Paul du Bois-Reymond (1831–1889), German mathematician
- Raoul Pene Du Bois (1914–1985), American film set and costume designer
- Victoire Du Bois (* 1988 or 1989), French actress
- WEB Du Bois (1868–1963), (also WE Burghard DuBois) American civil rights activist and sociologist
Du Bois means:
- Du Bois (car brand) , former British car brand
- Du Bois-Reymond , Berlin Huguenot family
See also:
- DuBois Island , off the west coast of Graham Land, Antarctica
- Dubois , Bois
