Ecdysteroids
Ecdysteroids are chemical compounds found as hormones in molting animals (ecdysozoa) such as spiders , crabs, and insects . These hormones formed in the prothorax gland, which include ecdysone and ecdysterone , control numerous physiological processes in these animals, such as moulting (ecdysis), metamorphosis or reproduction . These processes are at the molecular level via activation of the nuclear receptors counting ecdysone receptors and a selective activation of protein biosynthesis conveyed. Ecdysteroids and related substances are also produced by many plants as part of their defense against predators. Ecdysteroids ingested with food do not have a specific function in human or other mammals due to the lack of an ecdysone receptor. Due to the lack of its own receptors, the targeted introduction of ecdysone receptors and their activation with the help of ecdysteroids is used as a research tool in the biosciences. Regardless of this, unspecific effects due to the activation of other nuclear receptors are discussed. There is insufficient evidence for a declared therapeutic application, for example for muscle building.
Individual evidence
- ↑ Dinan L, Lafont R: Effects and applications of arthropod steroid hormones (ecdysteroids) in mammals . In: J. Endocrinol. . 191, No. 1, October 2006, pp. 1-8. doi : 10.1677 / joe.1.06900 . PMID 17065383 .
- ↑ Kreider RB, Wilborn CD, Taylor L, et al. : ISSN exercise & sport nutrition review: research & recommendations . In: J Int Soc Sports Nutr . 7, 2010, p. 7. doi : 10.1186 / 1550-2783-7-7 . PMID 20181066 . PMC 2853497 (free full text).