Self-brewing syndrome

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The Eigenbrauer Syndrome , also known as Auto-Brewery Syndrome or Gut Fermentation Syndrome , is a rare disease of the intestine .

If the immune system is weakened by poor nutrition or treatment with antibiotics , the microbiology of the intestine can be disrupted. Under certain circumstances yeasts can settle or multiply so strongly ( candidiasis ) that they set in motion an overpowering process of alcoholic fermentation . Liver-damaging alcohols such as ethanol , methanol or butanol are produced in the body , which lead to self-generated alcoholisation of the person concerned.

Long-term untreated disease can result in irreparable consequential damage to the liver ( cirrhosis ), the development of carcinogenic degradation products of dehydrogenase , and all risks of alcoholisation in everyday life or e.g. B. road traffic with the psychosocial consequences of ostracism in the social environment or criminal prosecution.

In the media

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The self-brewing syndrome is the topic of the television series Doc Martin in the episode "A Difficult Patient" of the 8th season. Also in the TV series In all Friendship - The Young Doctors Saffel 1, episode 8 "Apparent or Being", Grey's Anatomy Season 15, episode 3 "Gut feeling" and in the series The Good Doctor , season 3, episode 5 "Rescue Trust", the self-brewing syndrome is treated.

literature

  • Barbara Cordell, Justin McCarthy: A Case Study of Gut Fermentation Syndrome (Auto-Brewery) with Saccharomyces cerevisiae as the Causative Organism . In: Journal of Clinical Medicine , Vol. 4 No. 7, July 2013 ( online )
  • Fahad Malik, Prasanna Wickremesinghe, Jessie Saverimuttu: Case report and literature review of auto-brewery syndrome: probably an underdiagnosed medical condition. BMJ Open Gastroenterology 2019, 6: e000325, DOI: 10.1136 / bmjgast-2019-000325

Web links