Erythroplasia
| Classification according to ICD-10 | |
|---|---|
| D07 | Carcinoma in situ of other and unspecified genital organs |
| D07.1 | vulva |
| D07.4 | Penile erythroplasia Queyrat onA |
| ICD-10 online (WHO version 2019) | |
The Erythroplasia , Synonyms: Nacktpapilläres epithelioma; Queyrat syndrome or Erythroplasia de Queyrat (first described by Louis Auguste Queyrat, * December 2, 1856, Meymanat ( Creuse ), France; † October 18, 1933, Paris , French dermatologist), is a skin disease that occurs on the genitals and is triggered by human papilloma viruses which can lead to skin cancer ( precancerosis ). The mucosal variant of Bowen's disease is called Queyrat's erythroplasia.
Symptoms
Erythroplasia occurs primarily in uncircumcised men on the glans of the penis and its foreskin , but also in women on the labia and the oral mucosa : It is characterized by flat, sharply defined spots that are deep red in color and have a matt surface. The spots begin small and grow slowly but steadily and spread across the surface. Complaints are rare. The finding is fatally often overlooked or ignored for years.
histology
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Histologically, erythroplasia is a real carcinoma in situ , and is described as a mucosal variant of Bowen's disease , but in contrast to it only occurs on the genitals. If erythroplasia is suspected, a sample ( biopsy ) should be taken and the tissue should be examined in order to detect and treat skin cancer at an early stage.
therapy
Lesions are treated topically with 5-fluorouracil ointment, systemically with bleomycin . In the event of a relapse, the lesion must be completely removed and then covered with plastic. For use, the coming excision means Elektrotom that laser photocoagulation , the irradiation with soft X-rays or cryosurgery . In extreme cases, the glans must be amputated.
forecast
The prognosis is less favorable than that of Bowen's disease. Close controls are therefore necessary.
annotation
Erythroplasia is not to be confused with erythroplakia , a form of leukoplakia .
See also
Individual evidence
- ↑ Archive of the Institut Pasteur ( Memento of the original from October 23, 2013 in the Internet Archive ) Info: The archive link was inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice.
- ^ GS Gerber: Carcinoma in situ of the penis. In: The Journal of Urology . 151, 1994, pp. 829-833. PMID 8126803 . (Review).
- ↑ a b Erythroplasia Queyrat - Altmeyers Encyclopedia - Department of Dermatology . June 21, 2016 ( enzyklopaedie-dermatologie.de [accessed June 26, 2018]).
- ^ Peter Fritsch: "Dermatology and Venerology", Springer Verlag, 2nd edition 2004, ISBN 3-540-00332-0
- ↑ G. von Krogh, S. Horenblas: Diagnosis and clinical presentation of premalignant lesions of the penis. In: Scandinavian journal of urology and nephrology. Supplement. Number 205, 2000, pp. 201-214, ISSN 0300-8886 . PMID 11144899 . (Review).
